Characterization of the inflammatory response to severe COVID-19 illness

OJ McElvaney, NL McEvoy, OF McElvaney… - American journal of …, 2020 - atsjournals.org
… Given the role of immunometabolism in inflammatory cytokine regulation… immune cells
during severe COVID-19 illness. Finally, we assessed the acute phase antiinflammatory response

COVID-19 as an acute inflammatory disease

RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
… system, along with the inhibition of the adaptive immune response, makes COVID-19 deadly
for the elderly or individuals with underlying diseases, with men being more vulnerable than …

[HTML][HTML] Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
immune responses are implicated in the disease's progression to a more severe and lethal
process. … There is consensus that in severe COVID-19 infection, an exacerbated pulmonary …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
… dysregulated host immune response in COVID-19, identify … can be used to manage immune
dysregulation in COVID-19. … with severe disease and correlated with COVID-19 progression (…

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… Nevertheless, the ADE-mediated inflammatory response and association of pre-existing
antibodies with disease progression and severity in COVID-19 require further investigation. …

[HTML][HTML] Immune determinants of COVID-19 disease presentation and severity

P Brodin - Nature medicine, 2021 - nature.com
… know about the immune response to SARS-CoV-2 infection and how this might explain different
disease presentations and disease severity by considering … COVID-19 disease courses …

Mechanism of inflammatory response in associated comorbidities in COVID-19

TMC de Lucena, AF da Silva Santos… - Diabetes & Metabolic …, 2020 - Elsevier
… Diabetes, hypertension and other cardiovascular diseases (CVD) are strongly related to a
higher risk of mortality or disease’s severity among COVID-19 patients. In China, from 44,672 …

[HTML][HTML] COVID-19 infection: the perspectives on immune responses

Y Shi, Y Wang, C Shao, J Huang, J Gan… - Cell Death & …, 2020 - nature.com
… of coronavirus disease 2019, COVID-19, and its pathogenesis [1]: not all people exposed
to SARS-CoV-2 are infected and not all infected patients develop severe respiratory illness. …

[PDF][PDF] A dynamic immune response shapes COVID-19 progression

EZ Ong, YFZ Chan, WY Leong, NMY Lee… - Cell host & …, 2020 - cell.com
… in the early phase of illness, are indeed dynamic in … acute immune response to SARS
CoV-2 infection is dynamic, and this dynamism needs to be taken into consideration in COVID-19

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… systemic inflammatory response, … -inflammatory cytokines associated with COVID-19
outcome and their relationship with clinical manifestations involved in the severity of this disease. …