Tocilizumab in patients with moderate or severe COVID-19: a randomized, controlled, open-label, multicenter trial

D Wang, B Fu, Z Peng, D Yang, M Han, M Li, Y Yang… - Frontiers of …, 2021 - Springer
COVID-19 patients. We attempted to verify the effectiveness and safety of tocilizumab therapy
in COVID-… a randomized, controlled, open-label multicenter trial among COVID-19 patients. …

Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial

X Mariette, O Hermine, PL Tharaux… - The Lancet …, 2022 - thelancet.com
… Patients with COVID-19 pneumonia can have increased … of patients with moderate-to-severe
COVID-19 pneumonia. … in patients with moderate-to-severe COVID-19 pneumonia. Further …

Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study

E Della-Torre, C Campochiaro, G Cavalli… - Annals of the …, 2020 - ard.bmj.com
… sarilumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation.
Methods We conducted an open-label study of sarilumab in severe COVID-19 pneumonia (…

… low dose of dexamethasone on clinical worsening in patients hospitalised with moderate or severe COVID-19 pneumonia: an open-label, randomised clinical trial

M Taboada, N Rodríguez, PM Varela… - European …, 2022 - Eur Respiratory Soc
… We performed a randomised, open-label, controlled trial involving hospitalised patients
with confirmed COVID-19 pneumonia needing oxygen therapy. Patients were randomly …

Clinical and immunological benefits of convalescent plasma therapy in severe COVID-19: insights from a single center open label randomised control trial

Y Ray, SR Paul, P Bandopadhyay, R D'Rozario, J Sarif… - MedRxiv, 2020 - medrxiv.org
… from a single center open label phase II parallel arm randomised control trial done in a
single center in Eastern India, done on patients suffering from severe COVID-19 disease with …

An open-label randomized controlled trial evaluating the efficacy of chloroquine/hydroxychloroquine in severe COVID-19 patients

Á Réa-Neto, RS Bernardelli, BMD Câmara, FB Reese… - Scientific reports, 2021 - nature.com
… by the worsening clinical status of patients with severe COVID-19 evaluated on the 14th and
… Our trial enrolled severe COVID-19 patients who were receiving supplemental oxygen or MV…

… in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation (CYCOV): a single centre, open-label, randomised, controlled trial

A Supady, E Weber, M Rieder, A Lother… - The Lancet …, 2021 - thelancet.com
… -centre, open-label, randomised, controlled trial to investigate cytokine adsorption in adult
patients with severe COVID-19 pneumonia requiring ECMO. Patients with COVID-19 selected …

[HTML][HTML] Standard prophylactic versus intermediate dose enoxaparin in adults with severe COVID‐19: a multi‐center, openlabel, randomized controlled trial

US Perepu, I Chambers, A Wahab, P Ten Eyck… - Journal of thrombosis …, 2021 - Elsevier
… In a multi‐center, openlabel, randomized controlled trial of hospitalized adults with
severe COVID‐19, we found no significant differences in the safety or efficacy of standard …

[HTML][HTML] Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial

T Karampitsakos, O Papaioannou, P Tsiri… - Clinical Microbiology …, 2023 - Elsevier
Objective Randomized controlled trials comparing tocilizumab and baricitinib in patients with
coronavirus disease 2019 (COVID-19) are needed. This was an open-label, randomized …

A phase 2 single center open label randomised control trial for convalescent plasma therapy in patients with severe COVID-19

Y Ray, SR Paul, P Bandopadhyay, R D'Rozario… - Nature …, 2022 - nature.com
… We report here insights gathered from a single-center open-label phase II randomized
control trial done in Eastern India, on patients with severe COVID-19 disease with evidence for …