[HTML][HTML] Nirmatrelvir plus ritonavir: first approval

YN Lamb - Drugs, 2022 - Springer
… , nirmatrelvir plus ritonavir received authorization in the EU for use in the same indication.
Nirmatrelvir plus ritonavir is … in the development of nirmatrelvir plus ritonavir leading to its first …

[HTML][HTML] Nirmatrelvir plus ritonavir in COVID-19: a profile of its use

HA Blair - Drugs & Therapy Perspectives, 2023 - Springer
… -19 at high risk for progression to severe disease. The incidence of … nirmatrelvir plus ritonavir
than with placebo. The efficacy of … nirmatrelvir exposure; therefore, nirmatrelvir plus ritonavir

[HTML][HTML] VV116 versus nirmatrelvirritonavir for oral treatment of Covid-19

Z Cao, W Gao, H Bao, H Feng, S Mei… - … England Journal of …, 2023 - Mass Medical Soc
… plus 100 mg of ritonavir every 12 hours for 5 days… nirmatrelvirritonavir as the active
control for comparison with VV116 was based on the established superiority of nirmatrelvirritonavir

[HTML][HTML] Nirmatrelvir/ritonavir and molnupiravir in the treatment of mild/moderate COVID-19: results of a real-life study

I Gentile, R Scotto, N Schiano Moriello, B Pinchera… - Vaccines, 2022 - mdpi.com
… molnupiravir, while 43.2% received nirmatrelvir/ritonavir. Patients in the molnupiravir group
… had a higher rate of chronic heart disease than those treated with nirmatrelvir/ritonavir. Three …

[HTML][HTML] Population-based evaluation of the effectiveness of nirmatrelvirritonavir for reducing hospital admissions and mortality from COVID-19

KL Schwartz, J Wang, M Tadrous, BJ Langford… - Cmaj, 2023 - Can Med Assoc
severe COVID-19. Our objective was to evaluate the effectiveness of nirmatrelvirritonavir
in preventing severe … We compared patients treated with nirmatrelvirritonavir with patients …

[HTML][HTML] Effectiveness of nirmatrelvir-ritonavir for the treatment of patients with mild to moderate COVID-19 and at high risk of hospitalization: systematic review and …

KM Souza, G Carrasco, R Rojas-Cortés… - Plos one, 2023 - journals.plos.org
… COVID-19 and eligible for nirmatrelvir-ritonavir treatment, a systematic review …
nirmatrelvir-ritonavir. The objective of this study was to evaluate the performance of …

[HTML][HTML] Effectiveness of nirmatrelvirritonavir in preventing hospital admissions and deaths in people with COVID-19: a cohort study in a large US health-care system

JA Lewnard, JM McLaughlin, D Malden… - … Infectious Diseases, 2023 - thelancet.com
… In the USA, oral nirmatrelvirritonavir is authorised for use in patients aged 12 years …
severe disease and hospitalisation. We aimed to establish the effectiveness of nirmatrelvirritonavir

[HTML][HTML] Efficacy and safety of nirmatrelvir/ritonavir, molnupiravir, and remdesivir in a real-world cohort of outpatients with COVID-19 at high risk of progression: the …

G Tiseo, C Barbieri, V Galfo, S Occhineri… - Infectious Diseases and …, 2023 - Springer
… Adverse events occurred more frequently in the nirmatrelvir/ritonavir group (49.2%).
Nirmatrelvir/ritonavir compared with remdesivir was associated with a higher probability of having a …

Real-world effectiveness of nirmatrelvir/ritonavir in preventing hospitalization among patients with COVID-19 at high risk for severe disease in the United States: a …

X Zhou, SP Kelly, C Liang, L Li, R Shen… - medRxiv, 2022 - medrxiv.org
… The nirmatrelvir/ritonavir group included all patients meeting inclusion … nirmatrelvir/ritonavir;
the non-nirmatrelvir/ritonavir group included those not prescribed nirmatrelvir/ritonavir or …

[HTML][HTML] Real-world effectiveness of early molnupiravir or nirmatrelvirritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on …

CKH Wong, ICH Au, KTK Lau, EHY Lau… - … Infectious Diseases, 2022 - thelancet.com
… to nirmatrelvirritonavir use, or had severe renal or severe liver impairment were excluded.
Patients who received the oral antivirals molnupiravir or nirmatrelvirritonavir were matched …