[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and …
IL-6 levels that were not associated with elevations in other canonical proinflammatory cytokines

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… individual treatments for the cytokine storm in severe COVID-19. … (TPE) to treat cytokine
storm in severe COVID-19. We … of various immunosuppressive measures on cytokine storm are …

[PDF][PDF] Potential link between COVID-19 and periodontitis: cytokine storm, immunosuppression, and dysbiosis

GMC Fabri - Oral Health and Dental Management, 2020 - researchgate.net
… On the order hand, have been proposed a crucial role of cytokine storm in the pathogenesis
of severe acute respiratory syndrome coronavirus 2 of the genus Betacoronavirus (SARS…

Severe COVID-19: immunosuppression or hyperinflammation?

Y Liu, Y Li, D Xu, J Zhang, Z Peng - Shock, 2021 - journals.lww.com
… regulation of cytokines in … cytokine storms (38) . Correspondingly, an elevation in neutrophils
and white blood cells is thought to enhance cytokine release and promote cytokine storms

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
… signaling or PAMP/DAMP sensing causes inflammatory cell death that facilitates further
pathogenic cytokine release, culminating in a CS to drive severe, life-threatening damage to host …

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
cytokine storm. In this review, we referred COVID-19 associated cytokine storm as the patients
who are severely … binding to its receptor to exert the immunosuppression promoted by IL-6

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
cytokine storm in severe COVID-19. Therefore, here, we have discussed the current findings
and treatment strategies for the cytokine storm in severe … use of immunosuppressive drugs (…

[HTML][HTML] Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
… was to describe cytokine storm signatures in patients with acute COVID-19 and to investigate
their influence on severity of the infection. Plasma levels of 47 cytokines were investigated …

Immunotherapeutic implications of IL-6 blockade for cytokine storm

T Tanaka, M Narazaki, T Kishimoto - Immunotherapy, 2016 - Future Medicine
… the hyperinflammatory phase enter a protracted immunosuppressive phase, known as the
… that it is beneficial for a cytokine storm, an acute severe systemic inflammatory complication (…

[HTML][HTML] Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
… terminologies used to describe a severe, life-threatening condition … Institute defines cytokine
storm as a severe immune reaction … These natural immunosuppressive agents provide an …