[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… to cytokine storm respect others. Different genetic mutations may also represent a risk factor
for the severe disease course and the occurrence of cytokine storm … to immunosuppression. …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… CS are the cornerstone of treatments for cytokine storms and … may be useful in the more
severe forms of CRS to curb the … therapeutic regimens including immunosuppressive drugs, it …

[HTML][HTML] Immunotherapy summary for cytokine storm in COVID-19

Y Li, W Zhao, J Liu, Z Chen, Q Lv… - Frontiers in Pharmacology, 2021 - frontiersin.org
severe challenge to the global public health system but also brings huge economic losses to
the society. Virus infection can cause cytokine storm… due to immunosuppressive effects. High…

Weathering the cytokine storm in susceptible patients with severe SARS-CoV-2 infection

B Lipworth, R Chan, S Lipworth… - The Journal of Allergy …, 2020 - jaci-inpractice.org
… downstream immunosuppressive effects by reducing IL-6 … More severe COVID-19 infection
may produce a cytokine storm … , with IL-6 levels being highly predictive of respiratory failure. …

Immunosuppression in patients who die of sepsis and multiple organ failure

JS Boomer, K To, KC Chang, O Takasu, DF Osborne… - Jama, 2011 - jamanetwork.com
Severe sepsis is typically characterized by initial cytokine-mediated hyperinflammation.
Whether this hyperinflammatory phase is followed by immunosuppression is … or “cytokine storm,” …

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis

LK Weaver, EM Behrens - Current treatment options in rheumatology, 2017 - Springer
… As patients with cytokine storm physiology present acutely with severe organ dysfunction, …
Broad-spectrum immunosuppression leaves many cytokine storm patients susceptible to …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
… Clinical studies suggest excessive release of inflammatory mediators leads to cytokine storm,
a … The review also portrays a question and debates: Can targeting cytokine storm can be a …

[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
… contribute to cytokine storm, … severity of COVID-19. In addition, we provide a conceptual
framework for innate immunity driving cytokine storm and organ damage in patients with severe

[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
cytokines/chemokines production, called as cytokine storm, … with severe COVID-19 represent
the differential cytokine … taken before immunosuppressive therapy by cytokine blockers …

Persistent inflammation, immunosuppression, and catabolism and the development of chronic critical illness after surgery

PA Efron, AM Mohr, A Bihorac, H Horiguchi… - Surgery, 2018 - Elsevier
… SIRS or CARS response, or “cytokine storm,” is an appropriate mammalian reaction to an …
unique, and immunosuppressive to T lymphocytes after severe sepsis or septic shock in the …