[HTML][HTML] The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

ME Nassif, SL Windsor, BA Borlaug, DW Kitzman… - Nature medicine, 2021 - nature.com
… trial of patients with HFpEF (NCT03030235), we evaluated whether the SGLT2 inhibitor
dapagliflozin improves the primary endpoint of Kansas City Cardiomyopathy Questionnaire …

… the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular ejection fraction (DAPA …

JJV McMurray, DL DeMets, SE Inzucchi… - … of heart failure, 2019 - Wiley Online Library
… DAPA-HF will determine the efficacy and safety of the SGLT2 inhibitor dapagliflozin,
added to conventional therapy, in a broad spectrum of patients with heart failure and reduced …

[HTML][HTML] Dapagliflozin in patients with heart failure and reduced ejection fraction

JJV McMurray, SD Solomon, SE Inzucchi… - … England Journal of …, 2019 - Mass Medical Soc
… the DAPA-HF (Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure) trial to
… and safety of the SGLT2 inhibitor dapagliflozin in patients with heart failure and a reduced …

[HTML][HTML] Dapagliflozin in heart failure with mildly reduced or preserved ejection fraction

SD Solomon, JJV McMurray, B Claggett… - … England Journal of …, 2022 - Mass Medical Soc
… for heart failure or cardiovascular death among patients with heart failure and a left ventricular
… of SGLT2 inhibition may extend to all patients with heart failure, regardless of the left …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
… The key finding from these exploratory analyses of patients with heart failure with reduced
ejection fraction was that the effect of the SGLT2 inhibitor dapagliflozin on the primary and …

Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus

ET Kato, MG Silverman, O Mosenzon, TA Zelniker… - Circulation, 2019 - Am Heart Assoc
SGLT2 inhibition with dapagliflozin reduced the risk of cardiovascular death or HHF to a
greater extent in patients … reductions in cardiovascular death and ACM in patients with HFrEF. …

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

F Zannad, JP Ferreira, SJ Pocock, SD Anker, J Butler… - The Lancet, 2020 - thelancet.com
… of SGLT2 inhibition with dapagliflozin and empagliflozin on fatal events, hospitalisation
for heart failure, … clinical subgroups in a broad spectrum of patients with HFrEF. Our meta-analysis …

Efficacy and safety of dapagliflozin in patients with acute heart failure

ZL Cox, SP Collins, GA Hernandez, AT McRae III… - Journal of the American …, 2024 - jacc.org
… Early dapagliflozin initiation before patient stabilization on the first day of acute heart
failure (AHF) hospitalization was safe, allowing rapid guideline-directed medical therapy (GDMT) …

Dapagliflozin in Patients with Chronic Heart Failure: A Systematic Review and Meta‐Analysis

R Cai, Y Xu, Q Su - Cardiology research and practice, 2021 - Wiley Online Library
SGLT2 inhibitor dapagliflozin can reduce the cardiovascular death/hospitalization for heart
failure (CV death/HHF) in patients … FDA authorized dapagliflozin for adult patients with HFrEF (…

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… In the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening
heart failure (HF) and death in patients with HF and reduced ejection fraction. We examined …