[HTML][HTML] The sodium-glucose co-transporter 2 inhibitor dapagliflozin improves prognosis in systolic heart failure independent of the obesity paradox

S Carbone, CJ Lavie - European journal of heart failure, 2021 - ncbi.nlm.nih.gov
… Effects of the SGLT2 inhibitor dapagliflozin on energy metabolism in patients with type 2
diabetes: a randomized, double-blind crossover trial. Diabetes Care 2021;44:1334–1343. [PMC …

The Dapagliflozin and Prevention of Adverse outcomes in Heart Failure trial (DAPA-HF) in context

JJV McMurray, SD Solomon, KF Docherty… - European Heart …, 2021 - academic.oup.com
… (SGLT2) inhibitor dapagliflozin reduced the risk of hospital admission for worsening heart
failure, … and at much higher cardiovascular risk than patients in the prior SGLT2 inhibitor trials. …

Kidney and heart failure outcomes associated with SGLT2 inhibitor use

AB van der Aart-van der Beek, RA de Boer… - Nature Reviews …, 2022 - nature.com
SGLT2 inhibition in patients with heart failure were provided by the Effect of Sotagliflozin on
Cardiovascular Events in PatientsSGLT2 inhibitor (in this case dapagliflozin) on mortality in …

Effects of dapagliflozin on cardiovascular events, death, and safety outcomes in patients with heart failure: a meta-analysis

XD Zheng, Q Qu, XY Jiang, ZY Wang, C Tang… - … of Cardiovascular Drugs, 2021 - Springer
… Effects of empagliflozin on risk for cardiovascular death and heart failure hospitalization
across the spectrum of heart failure risk in the EMPA-REG OUTCOME(R) trial. Eur Heart J. 2018;…

Positive effect of dapagliflozin on left ventricular longitudinal function for type 2 diabetic mellitus patients with chronic heart failure

H Tanaka, F Soga, K Tatsumi, Y Mochizuki… - Cardiovascular …, 2020 - Springer
… the SGLT2 inhibitor dapagliflozin on LV diastolic functional parameters of T2DM patients with
… and 6 months after administration of dapagliflozin. LV diastolic function was defined as the …

[HTML][HTML] DAPA-HF trial: dapagliflozin evolves from a glucose-lowering agent to a therapy for heart failure

E Kaplinsky - Drugs in Context, 2020 - ncbi.nlm.nih.gov
… the SGLT2 inhibitor dapagliflozin was added to a guideline-directed therapy. This marks a
dramatic evolution of this particular agent (feasibly extensible to others) from being initially a …

Dapagliflozin for heart failure with preserved ejection fraction: will the DELIVER study deliver?

DM Williams, M Evans - Diabetes Therapy, 2020 - Springer
… Here, we discuss the use of SGLT2 inhibitors for heart failure with a focus on dapagliflozin
This may explain how SGLT2 inhibitor-mediated diuresis improves heart failure outcomes also…

Dapagliflozin in myocardial infarction without diabetes or heart failure

S James, D Erlinge, RF Storey, DK McGuire… - NEJM …, 2024 - evidence.nejm.org
SGLT2 inhibitor trials and shows clinically relevant, largely cardiometabolic, benefits of
dapagliflozin in patients … Importantly, patients with any degree of globally or regionally impaired …

Cardiovascular outcome in patients treated with SGLT2 inhibitors for heart failure: a meta-analysis

GM Gager, G Gelbenegger, B Jilma… - … in cardiovascular …, 2021 - frontiersin.org
… type of SGLT2 inhibitor used (empagliflozin, dapagliflozin, … that some patients with present
heart failure were undiagnosed. … most common SGLT2 inhibitors empagliflozin, dapagliflozin, …

Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial

DZI Cherney, CCJ Dekkers, SJ Barbour… - The lancet Diabetes & …, 2020 - thelancet.com
… in cardiovascular disease or kidney disease with several commercial organisations. RTG
has consulting agreements with AstraZeneca, Bayer, Sanofi–Genzyme, and Mundi Pharma; all …