… (10) use the transcriptome dataset approach to discover that SARS-CoV-2 can activate
apoptosis and P53 signaling pathway (one of the pathways responsible for the survival of the cell…

… most relevant cell types and signaling pathways responsible for disease pathology in vivo
have yet to be determined and understanding how the cytokine storm progresses in vivo will …

… ACE2 and AT1R leading to the cytokine storm progression. b) Produced IFNs-I bind to the
related receptors and launching their signaling pathways results in the nuclear translocation of …

… (S1P 1 R) signaling is primarily responsible for blunting cytokine storm to protect the infected
… host innate signaling pathways of cytokine storm and chart where along those pathways the …

… This review aims to summarize the pathophysiology of the cytokine storm; to describe the type,
effects, and kinetics of cytokine production; … Its signaling pathway goes through Raf-1 [31]. …

… IL-6 in the toll-like receptor signaling pathway might influence the immune system as the
downstream effector (53, 54, 58). Therefore, the dysregulation of ACE2 induced by SARS-CoV-…

… receptor (IL-6R) (probably via the nuclear factor kappa-B and STAT3 signaling pathway).
Tocilizumab seemed to be effective in COVID-19 patients, which decreased the use of …

… signaling pathways will be activated [84]. The corresponding adaptor molecules such as
IL-1 receptor-associated kinase 1 (RAK-1) and tumor necrosis factor receptor-associated factor …

… Cytokines allow context-dependent communication within … lead to cytokine production are
destabilized, a "cytokine storm" (… and IL12 as either, depending on the signaling pathway [21]. …

… TRIF signaling is primarily involved in the production of IFNs to … signaling pathways and
reduced production of cytokines in response to SARS-CoV-2 E protein [18]. The level of IL-6 in …