PI3K/AKT signaling pathway: a possible target for adjuvant therapy in COVID-19

MR Khezri - Human Cell, 2021 - Springer
… /AKT signaling pathway has been linked to the induction of lung tissue fibrosis, which has
been detected in patients with COVID-19 [5, 7]. Regarding the role of this pathway in inducing …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… We also discuss the induction, function, downstream signaling, and existing and potential …
related signal pathways. We believe that a comprehensive understanding of CS in COVID-19

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
… Given the elicited signaling pathways, we introduced possible pathway-based therapeutic
… of several signaling pathways involved in the immunopathogenesis of COVID-19. We also …

Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy

T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
… responsible for the immunopathology of COVID-19 and acute respiratory distress syndrome.
… IL-17A signaling and the synergic inflammatory cytokine IL-6 to manage COVID-19 patients, …

COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
… is observed in COVID-19. These findings … signaling pathways and pulmonary fibrosis.
The study consisted of 24 paraffin lung samples from patients who died of COVID-19 (COVID-19

The potential involvement of JAK-STAT signaling pathway in the COVID-19 infection assisted by ACE2

J Luo, S Lu, M Yu, L Zhu, C Zhu, C Li, J Fang, X Zhu… - Gene, 2021 - Elsevier
… for the study of COVID-19 infection. In this study, we demonstrated the expression features
of ACE2 in coronavirus infection and identified associated pathways of COVID-19 using gene …

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

DS Battagello, G Dragunas, MO Klein… - Clinical …, 2020 - portlandpress.com
… -coronavirus members. To better understand the development and transmission of COVID-19,
unveiling the signaling pathways … of cellular interaction and signaling pathways, elicited by …

NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients

R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
… lethality in COVID-19. The present perspective places a central cellular pro-inflammatory
signal pathway, NF-κB, in the context of recently published data for COVID-19 and provides a …

Janus kinase signaling pathway and its role in COVID-19 inflammatory, vascular, and thrombotic manifestations

JD Ravid, O Leiva, VC Chitalia - Cells, 2022 - mdpi.com
… Manifestations of Coronavirus Disease-19 Coronavirus Disease-19 (COVID-19) is a
worldwide public health crisis caused by the severe acute respiratory syndrome coronavirus 2 (…

SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19

DAB Rex, S Dagamajalu, RK Kandasamy… - … and Signaling, 2021 - Springer
… of signaling molecules will be helpful for COVID-19 research. Therefore, we developed the
signaling pathway … This integrated signaling pathway map of SARS-CoV-2 consists of 326 …