Effects of Silver Nanoparticles on the Liver and Hepatocytes In Vitro

BK Gaiser, S Hirn, A Kermanizadeh… - Toxicological …, 2013 - academic.oup.com
… Therefore, this study used a simple hepatocytes model combined with an in vivo injection …
human hepatocyte cell line C3A. We found that Ag NPs were highly cytotoxic to hepatocytes (…

Silver nanoparticles (AgNPs) and AgNO3 perturb the specification of human hepatocyte-like cells and cardiomyocytes

B Hu, N Yin, R Yang, S Liang, S Liang… - Science of the total …, 2020 - Elsevier
Silver nanoparticles (AgNPs) are commonly utilized industrial compounds mostly because
of their antimicrobial properties. Nevertheless, our understanding of their potential …

Comparison of in vitro toxicity of silver ions and silver nanoparticles on human hepatoma cells

IV Vrček, I Žuntar, R Petlevski, I Pavičić… - Environmental …, 2016 - Wiley Online Library
… the potential harmful effects of silver nanoparticles (AgNPs) on human health severely lags
… affect the level of albumin synthesis in hepatocytes. The human hepatoma-derived cell line, …

Comparative proteomic analysis reveals the different hepatotoxic mechanisms of human hepatocytes exposed to silver nanoparticles

TY Wong, N Yan, KKL Kwan, Y Pan, J Liu… - Journal of Hazardous …, 2023 - Elsevier
… After exposing 2.5 μg/mL Cit-AgNPs to hepatocytes for 24 h, we washed … human hepatocytes
exposed to Cit-AgNPs To study the AgNPs-induced hepatotoxicities in human hepatocytes, …

Effect of silver nanoparticles in the induction of apoptosis on human hepatocellular carcinoma (HepG2) cell line

E Ahmadian, SM Dizaj, E Rahimpour… - Materials Science and …, 2018 - Elsevier
… In addition, according to some in vivo and in vitro experiments silver nanoparticles
induce … mechanisms of silver nanoparticles in liver hepatocellular carcinoma cell line (HepG2). …

Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media

Y Xue, T Zhang, B Zhang, F Gong… - Journal of Applied …, 2016 - Wiley Online Library
… HepG2 cells are a suitable in vitro model system for the study of polarized human hepatocytes,
as the cells secrete a variety of major plasma proteins, which are important for the study …

[HTML][HTML] Transcriptomic and proteomic responses of silver nanoparticles in hepatocyte-like cells derived from human induced pluripotent stem cells

X Gao, R Li, JJ Yourick, RL Sprando - Toxicology in Vitro, 2022 - Elsevier
Silver nanoparticles (AgNPs) have been increasingly used in a variety of consumer
products over the last decades. However, their potential adverse effects have not been fully …

Nuclear translocation of silver ions and hepatocyte nuclear receptor impairment upon exposure to silver nanoparticles

VT Suárez, E Karepina, M Chevallet, B Gallet… - Environmental …, 2020 - pubs.rsc.org
The impact on human health of long-term exposure to low doses of silver nanoparticles (AgNPs)
remains understudied. Cellular studies have shown the intracellular dissolution of …

Visualization, quantification and coordination of Ag+ ions released from silver nanoparticles in hepatocytes

G Veronesi, A Deniaud, T Gallon, PH Jouneau… - Nanoscale, 2016 - pubs.rsc.org
Silver nanoparticles (AgNPs) can enter eukaryotic cells and … nanoprobe, silver is visualized
and quantified in hepatocytes (… nanoparticular and ionic forms of silver within a single cell. …

Concentration-dependent toxicogenomic changes of silver nanoparticles in hepa t ocyte-like cells derived from human induced pluripotent stem cells

X Gao, R Li, RL Sprando, JJ Yourick - Cell biology and toxicology, 2021 - Springer
… Primary human hepatocytes (PHHs) have been considered the gold standard for in vitro
hepatotoxicity studies, as these cells retained the expression of a comprehensive set of …