Acute toxic effects and gender‐related biokinetics of silver nanoparticles following an intravenous injection in mice

Y Xue, S Zhang, Y Huang, T Zhang… - Journal of Applied …, 2012 - Wiley Online Library
… This study evaluated the acute toxicity and biokinetics of intravenously administered silver
nanoparticles (AgNPs) in mice. Mice were exposed to different dosages of AgNPs (7.5, 30 or …

Silver nanoparticles induced oxidative and endoplasmic reticulum stresses in mouse tissues: implications for the development of acute toxicity after intravenous …

R Chen, L Zhao, R Bai, Y Liu, L Han, Z Xu… - Toxicology …, 2016 - academic.oup.com
… Immunotoxicity of silver nanoparticles was evaluated in rats by adopting the 28-day … In
this study, the adverse effects of intravenously administered AgNPs were investigated in Balb/c …

A pilot toxicology study of biogenic silver nanoparticles: in vivo by intraperitoneal and intravenous infusion routes in rats

C Ashajyothi… - Journal of Experimental …, 2019 - Taylor & Francis
… In case of silver nanotoxicity, hydrogen peroxide generated in vivo will react with silver
nanoparticles … In biological evaluation, intravenous administration of nanoparticles is also another …

Acute hazard assessment of silver nanoparticles following intratracheal instillation, oral and intravenous injection exposures

A Kermanizadeh, NR Jacobsen, A Mroczko… - …, 2021 - Taylor & Francis
… In this study, we demonstrate that IV administrationnanoparticles was clear in the target
organs, with the liver and the spleen accumulating largest quantities of Ag. The IT administration

Intravenous administration of silver nanoparticles causes organ toxicity through intracellular ROS-related loss of inter-endothelial junction

H Guo, J Zhang, M Boudreau, J Meng, J Yin… - Particle and fibre …, 2015 - Springer
Background Administration of silver nanoparticles (AgNPs) to mice could result in their
distribution and accumulation in multiple organs, with notable prominence in liver, lungs, and …

… and hematological study after subacute intravenous injection of gold and silver nanoparticles and coadministered gold and silver nanoparticles of similar sizes

JH Lee, M Gulumian, EM Faustman… - BioMed research …, 2018 - Wiley Online Library
… To investigate the effect of subacute intravenous administration AgNP (silver nanoparticles,
10 nm) and AuNP (gold nanoparticles, 12.8 nm) and AgNP/AuNP mixture to blood …

[HTML][HTML] Systemic and immunotoxicity of silver nanoparticles in an intravenous 28 days repeated dose toxicity study in rats

WH De Jong, LTM Van Der Ven, A Sleijffers… - Biomaterials, 2013 - Elsevier
… lung and GI-tract, we used intravenous administration of nanosilver to evaluate its potential
… a repeated dose toxicity study after intravenous administration for 28 days. Special emphasis …

Sub-acute intravenous administration of silver nanoparticles in male mice alters Leydig cell function and testosterone levels

TX Garcia, GMJ Costa, LR França, MC Hofmann - Reproductive Toxicology, 2014 - Elsevier
… -term, in vivo exposure to silver nanoparticles (AgNPs) could be toxic to male reproduction.
Low dose (1 mg/kg/dose) AgNPs were intravenously injected into male CD1 mice over 12 …

Systemic and behavioral effects of intranasal administration of silver nanoparticles

LL Davenport, H Hsieh, BL Eppert, VS Carreira… - Neurotoxicology and …, 2015 - Elsevier
… Use of silver nanoparticles (AgNPs) for their antimicrobial properties is widespread. Much
of … conducted in vitro or following oral or intravenous administration in vivo. Intranasal (IN) …

Serum kinetics, distribution and excretion of silver in rabbits following 28 days after a single intravenous injection of silver nanoparticles

Y Lee, P Kim, J Yoon, B Lee, K Choi, KH Kil… - Nanotoxicology, 2013 - Taylor & Francis
… by a single oral or intravenous administration of either 1 or … After oral administration, most
of the silver was found in feces … with a single intravenous injection of AgNPs, silver was also …