[HTML][HTML] Dissecting the global dynamic molecular profiles of human fetal kidney development by single-cell RNA sequencing

P Wang, Y Chen, J Yong, Y Cui, R Wang, L Wen… - Cell reports, 2018 - cell.com
kidney development, we applied single-cell RNA sequencing (scRNA-seq) to >3,000 renal
cells … We classified the major cell types found in human fetal kidneys and defined their gene …

Determination of the dynamic cellular transcriptional profiles during kidney development from birth to maturity in rats by single-cell RNA sequencing

F Ding, X Tian, J Mo, B Wang, J Zheng - Cell Death Discovery, 2021 - nature.com
… , by using the scRNA-seq technique, we analyzed 54,704 rat kidney cells from just after birth
… stages of kidney development. Twenty-five original clusters and 13 different cell types were …

Psychrophilic proteases dramatically reduce single-cell RNA-seq artifacts: a molecular atlas of kidney development

M Adam, AS Potter, SS Potter - Development, 2017 - journals.biologists.com
development The CAP-generated single-cell RNA-seq data in this article provide a high-resolution
atlas of the gene expression programs driving kidney development. This is a useful …

Single-cell RNA sequencing for the study of development, physiology and disease

SS Potter - Nature Reviews Nephrology, 2018 - nature.com
… Many thousands of the single cells are then used for single-cell RNA sequencing (scRNA-seq)
gene … that drive normal embryonic kidney development, stem cells can be induced to form …

Single-cell RNA sequencing reveals mRNA splice isoform switching during kidney development

Y Wineberg, TH Bar-Lev, A Futorian… - Journal of the …, 2020 - journals.lww.com
… an additional layer of cellular heterogeneity that Drop-seq technology cannot … single-cell
RNA sequencing was used to characterize alternative splicing in the mouse embryonic kidney, …

Single-cell RNA sequencing of human kidney

J Liao, Z Yu, Y Chen, M Bao, C Zou, H Zhang, D Liu… - Scientific data, 2020 - nature.com
kidney, we rapidly obtained a single-cell suspension of the kidney and conducted single-cell
RNA sequencing (… With the development of next-generation sequencing, high-throughput …

Single cell dissection of early kidney development: multilineage priming

EW Brunskill, JS Park, E Chung, F Chen… - …, 2014 - journals.biologists.com
single cell RNA-seq strategy to create an atlas of gene expression patterns in the developing
kidney… In this report, we extend the kidney development atlas to single cell resolution. At …

Targeted single-cell RNA-seq identifies minority cell types of kidney distal nephron

L Chen, CL Chou, MA Knepper - Journal of the American Society …, 2021 - journals.lww.com
… , one possible explanation for the heterogeneity could be reciprocal mutual inductions
between nephron progenitors and ureteric bud during kidney development. Among DCT1 …

[HTML][HTML] The promise of single-cell RNA sequencing for kidney disease investigation

H Wu, BD Humphreys - Kidney international, 2017 - Elsevier
… Barriers for entry into this field are relatively low, and we suggest that there are unique
opportunities to apply scRNA-seq to better understand kidney development, homeostasis, and …

Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine

Y Wang, Y Zhao, Z Zhao, D Li, H Nie, Y Sun… - … & Cell, 2021 - academic.oup.com
… During fetal mouse kidney development, SOX9 is expressed within the ureteric tip since the
earliest stages, and is required for ureter branching as well as maintaining ureteric tip identity…