… COVID-19 (coronavirus disease 2019) pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2… The trimeric spike (S) protein of the virus decorates the viral …

… Coronavirus spike (S) glycoproteins promote entry into cells and are … SARS-CoV-2 S uses
ACE2 to enter cells and that the receptor-binding domains of SARS-CoV-2 S and SARS-CoV …

… In summary, we have used authentic SARS-CoV-2 to demonstrate that the spike D614G
substitution enhances viral replication in the upper respiratory tract and increases the …

SARS-CoV-2 infection is associated with a surprising … the amyloidogenicity of the SARS-CoV-2
spike protein (S-protein). … Three 20-amino acid long synthetic spike peptides (sequence …

The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide,
reaching near fixation in a matter of months. Here we show that D614G was more infectious …

… In addition to documenting the emergence of SARS-CoV-2 Spike ΔH69/ΔV70 in vivo, we
show that this mutation increases infectivity of the Spike protein in a pseudotyping assay. The …

… Throughout the COVID-19 pandemic, epidemiologists have monitored the evolution of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with particular focus on the spike …

… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The trimeric viral spike
(S) … These findings advance our understanding of SARS-CoV-2 entry and may guide the …

… distributions compared to the unmutated spike. The most pronounced changes … 2 RBDs
in the up position, which has been reported before for the SARS-CoV-1 and MERS CoV spike …

… Spike-specific monoclonal antibody neutralization is … spike pseudotypes, but potency is
reduced in a minority of samples. This work highlights that changes in SARS-CoV-2 spike can …