… version of the SARS-CoV-2 spike protein ectodomain with a set of stabilizing mutations (…
The G614 spike protein was produced very similarly to the D614 spike we described before (…

… We and others have reported structures of a purified, full-length D614 S protein in both
prefusion and postfusion conformations (19, 20). Studies by cryo–electron tomography (cryo-ET), …

… significantly higher density of incorporated S protein than S(D614) VLPs, when same … protein
band intensity [35]. We also observed higher incorporation of S(G614) compared to S(D614…

… D614 and … spike (S) protein are central to the variants and might increase the viral infection
rate. The mechanism that underlines various mutations and how they might alter the S-protein …

… We immunoprecipitated D614 and G614 Spike protein from HEK293FT cell lysates and then
performed on-bead digestion using different concentrations of purified furin protease. Over …

… 614 in the spike protein (D614). This … D614 to G614 occurred asynchronously in different
regions throughout the world, including even local epidemics where the wildtype (WT) D614 …

… mutation in the viral spike (S) protein predominate over time in … of the S proteins with aspartic
acid (S D614 ) and glycine (S … efficiently than those with S D614 . This greater infectivity …

… Using a pseudovirus-based assay, we identified that S-D614 and S-G614 protein
pseudotyped viruses share a common receptor, human angiotensin-converting enzyme 2 (ACE2), …

… the spike protein variant D614G. A23403G was first reported at the end of January 2020 in
virus genomes from China and Germany. Given how few SARS-CoV-2 genomes have been …

… We transfected both D614 and G614 Spike variants into human HEK293FT cells to see …
The kinetics of the D614 and G614 Spike protein variants with hACE2 were analyzed using bio-…