H Lim, SE Kim, YH Lee, YH Hwang, SH Kim, MY Kim… - Virology, 2022 - Elsevier
… with the needs of vaccine, we developed four DNAvaccine candidates against SARS-CoV-2, based on the full-length spike (S) or truncated S protein. Following mice vaccination, we …
MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
… The bacTRL-Spikevaccine uses live, recombinant Bifidobacterium longum that contains synthetic plasmid DNA encoding the S protein of SARS-CoV-2. Bifidobacterium is a …
K Muthumani, D Falzarano, EL Reuschel… - Science translational …, 2015 - science.org
… the lack of approved antiviral therapies or vaccines to treat or prevent this infection are … DNAvaccine against MERS-CoV. An optimized DNAvaccine encoding the MERS spikeprotein …
D Tatlow, C Tatlow, S Tatlow… - Clinical and Experimental …, 2020 - Wiley Online Library
… In this paper the primary use of an inhaled plasmid DNAvaccine containing the coronavirus spikeproteinDNA sequence is for treatment. The small chitosan plasmid DNA size of …
… Traditional inactivated vaccines, mRNA vaccines (protein subunits such as spike … the DNA vaccines for Covid - 19. This article tried to explore the available information on DNAvaccines …
… 1 (S1) of the spikeprotein represents an attractive immunogen for vaccine development. Here, we developed and assessed the immunogenicity of a DNAvaccine encoding the SARS-…
J Chen, B Huang, Y Deng, W Wang, C Zhai, D Han… - Vaccines, 2023 - mdpi.com
… In this study, co-immunization with two DNAvaccines expressing the S and N proteins induced high … DNAvaccines expressing the S protein induced increased S protein-specific cellular …
… This article provides a brief overview of DNAvaccines. First, the basic DNAvaccine design … The spike (S) protein of SARS-CoV-2 is the main antigen used in preclinical and clinical …
TRF Smith, A Patel, S Ramos, D Elwood, X Zhu… - Nature …, 2020 - nature.com
… engineered a synthetic DNAvaccine targeting the MERS coronavirus Spike (S) protein, the major … Here we build on this prior experience to generate a synthetic DNA-based vaccine …