… Introduction: The continual Middle East respiratory syndrome (MERS) threat highlights the …
treat MERS coronavirus (MERS-CoV) infection. A surface spike (S) protein guides MERS-CoV …

… MERS-CoV infection. Here we discuss the most recent studies on the structure of … MERS-CoV
spike protein and its role in virus binding and entry, and the development of MERS-CoV …

… The MERS-CoV spike (S) protein is an … of the S protein in the MERS-CoV life cycle, summarize
recent advances in the development of vaccines and therapeutics based on the S protein, …

… novel antiviral strategies to combat MERS. The MERS-CoV spike protein (MERS-S) is inserted
into the viral envelope and mediates viral entry into target cells. For this, MERS-S binds to …

… the S protein or receptor, which allow MERS-CoV to … protein shown to be critical for DPP4
binding and viral entry. This information is crucial to understand the adaptation of MERS-CoV …

… Middle East respiratory syndrome coronavirus (MERS-CoV) is … To date, MERS-CoV continues
to infect humans with a fatality … The MERS-CoV surface spike (S) protein is a key target for …

Middle East Respiratory Syndrome coronavirus (MERS-CoV) causes severe pulmonary
infection, with ∼35 % mortality. Spike glycoprotein (S) of MERS-CoV is a key target for vaccines …

… remain over protein or full-length spike (S) protein-based … expressing different fragments of
MERS-CoV S protein in mice. We … S1-subunit of the MERS-CoV S protein could represent a …

… A key step in the MERS-CoV replication cycle is the fusion of the virus and host cell … by
the virus spike protein, S. The location of the fusion peptide within the MERS S protein has not …

… are involved in binding the MERS-CoV spike protein revealed that these animal species
are more likely able to use DPP4 as a functional receptor for MERS-CoV entry as compared to …