… Upon engagement of ACE2 by a receptor binding domain (RBD) in S1 (13), conformational
rearrangements occur that cause S1 shedding, cleavage of S2 by host proteases, and …

… human angiotensin-converting enzyme 2 (hACE2) receptor for cellular entry. To identify
residues in the spike protein … the hACE2 receptor and subsequently mapped a minimal receptor-…

… receptor-binding domain (RBD) of the spike protein, has risen to intense scientific and public
attention. Here, we studied the binding properties between the human receptor ACE2 (… RBD-…

… spike protein has become the most investigated target due to its ability in forming interactions
with the human ACE2 receptor… the human ACE2-SARS-CoV-1 spike-RBD protein complex (…

… to quantify the specific interactions between SARS-CoV-2 or SARS-CoV-1 receptor-binding
domain and human ACE2. The study reveals the mechanism behind the difference in …

… receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 bound to the cell receptor
ACE2. … The SARS-CoV-2 RBD and the N-terminal peptidase domain of human ACE2 were …

… SARS-CoV-2 virus Spike protein receptor binding domain (RBD) and the ACE2 cell surface
protein is required for viral infection of cells. Mutations in the RBD are present in SARS-CoV-…

… receptor-binding domain (RBD) of coronavirus spike protein and the host receptor,
angiotensin-converting enzyme 2 (ACE2). … -2 spike RBD and human ACE2 or other hosts' …

… bat SARS-like CoV RBD suggests it is too 217 high to bind human ACE2 effectively (KD in …
to human ACE2 at the micromolar range, just ~6x higher than that of 219 human SARS virus (…

… receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 interacts with the human
angiotensin-converting enzyme 2 (ACE2) receptor… interactions between ACE2 and RBD of …