Decrease in the generation of amyloid-β due to salvianolic acid B by modulating BACE1 activity
S Sundara Kumar Durairajan… - Current Alzheimer …, 2017 - ingentaconnect.com
… Recent studies suggest that salvianolic acid B (Sal B) is isolated … In addition, using
protein-docking, we determined the … Sal B are represented by red spikes. The active site residues …
protein-docking, we determined the … Sal B are represented by red spikes. The active site residues …
Salvianolic acid B protects against pulmonary fibrosis by attenuating stimulating protein 1‐mediated macrophage and alveolar type 2 cell senescence
Y Li, R Chen, J Wu, X Xue, T Liu, G Peng… - Phytotherapy …, 2024 - Wiley Online Library
… Network pharmacology analysis predicts potential targets for salvianolic acid B (SAB) in
the treatment of idiopathic pulmonary fibrosis (IPF). (a) The Venn graph of co-differentially …
the treatment of idiopathic pulmonary fibrosis (IPF). (a) The Venn graph of co-differentially …
[HTML][HTML] Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry
D Zhang, S Hamdoun, R Chen, L Yang, CK Ip… - Pharmacological …, 2021 - Elsevier
… proteins, structural proteins and non-structural proteins. The structural proteins include the
spike protein (S), matrix protein … that salvianolic acid A, B and C can inhibit SARS-CoV-2 spike …
spike protein (S), matrix protein … that salvianolic acid A, B and C can inhibit SARS-CoV-2 spike …
Exploitation of some natural products for the prevention and/or nutritional treatment of SARS-CoV2 infection
A Rizzo, RL Sciorsci, T Magrone… - Endocrine, Metabolic & …, 2021 - ingentaconnect.com
… at the cellular surface [6] and disrupting spikes proteins [35]. … Some active agents (caffeic
acid and salvianolic acid), either … act as inhibitors of viral replication proteins such as reverse …
acid and salvianolic acid), either … act as inhibitors of viral replication proteins such as reverse …
[HTML][HTML] Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies
… protein and each side of the 3D box. Under periodic boundary conditions implementation,
the protein … all heavy atoms and preserving original protein folding. The first stage involved …
the protein … all heavy atoms and preserving original protein folding. The first stage involved …
[HTML][HTML] Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19
Y Yi, M Zhang, H Xue, R Yu, YO Bao, Y Kuang… - … Pharmaceutica Sinica B, 2022 - Elsevier
… of spike protein and the interaction between the ACE2 receptor and S1-RBD, respectively.
Recently, Su et al. reported that myricetin (EC 50 , 8.0 μmol/L) and dihydromyricetin (EC 50 , …
Recently, Su et al. reported that myricetin (EC 50 , 8.0 μmol/L) and dihydromyricetin (EC 50 , …
Computational studies evidenced the potential of steroidal lactone to disrupt surface interaction of SARS-CoV-2 spike protein and hACE2
A Yadav, MD Ojha, P Hariprasad - Computers in Biology and Medicine, 2022 - Elsevier
… Salvianolic acid (a dimer of caffeic acid) [26], cepharanthine (bisbenzylisoquinoline alkaloid),
colforsin (a forskolin derivative for Coleus forskohlii) and ingenol (from Euphorbia peplus) […
colforsin (a forskolin derivative for Coleus forskohlii) and ingenol (from Euphorbia peplus) […
Targeting the SARS-CoV-2 HR1 with small molecules as inhibitors of the fusion process
… In this paper, we studied the spike protein S2 domain of … interest are ZINC00097961973,
Salvianolic acid, Thalassiolin A … compounds, among them Salvianolic acid, recently reported for …
Salvianolic acid, Thalassiolin A … compounds, among them Salvianolic acid, recently reported for …
Discovery and structural optimization of 3-O-β-chacotriosyl oleanane-type triterpenoids as potent entry inhibitors of SARS-CoV-2 virus infections
H Li, C Cheng, S Li, Y Wu, Z Liu, M Liu, J Chen… - European Journal of …, 2021 - Elsevier
… The spike protein of SARS-CoV-2 is consisted of S1 and S2 subunits, which is responsible
for recognition of host cells and virus-cell membrane fusion, respectively. To investigate the …
for recognition of host cells and virus-cell membrane fusion, respectively. To investigate the …
[HTML][HTML] Screening of drug databank against WT and mutant main protease of SARS-CoV-2: Towards finding potential compound for repurposing against COVID-19
… The Spike protein (S), RNA-dependent RNA polymerase (… These mutations within the active
site of these target proteins … Salvianolic acid A, an antioxidant molecule extracted from S. …
site of these target proteins … Salvianolic acid A, an antioxidant molecule extracted from S. …