Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential

N Song, M Scholtemeijer, K Shah - Trends in pharmacological sciences, 2020 - cell.com
… Previous studies have confirmed that the immunomodulatoryimmunomodulatory potential,
in which regulatory T cells and monocytes play a key role. We review the immunomodulatory

Mesenchymal stem cell‐based immunomodulation: properties and clinical application

M Wang, Q Yuan, L Xie - Stem cells international, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells characterized by self‐renewal,
production of clonal cell populations, and multilineage differentiation. They exist in nearly all …

Mesenchymal stem cells and immunomodulation: current status and future prospects

F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
immunomodulatory properties of mesenchymal stem cells (MSCs) make them an invaluable
cell … mechanisms of MSC-based transplantation for immunomodulation. In this review, we …

Immunomodulatory effects of stem cells

N Wada, S Gronthos, PM Bartold - Periodontology 2000, 2013 - Wiley Online Library
… stromal-cell lineages. Recently, the immunomodulatory properties of mesenchymal stem
cells have attracted interest as a unique property of these cells that may be harnessed for novel …

Immunomodulation by mesenchymal stem cells and clinical experience

K Le Blanc, O Ringden - Journal of internal medicine, 2007 - Wiley Online Library
… They inhibit T-cell proliferation to alloantigens and mitogens and prevent the development
… T-cells. In vivo, MSCs prolong skin allograft survival and have several immunomodulatory

Immunomodulation by neural stem cells

T Ben-Hur - Journal of the neurological sciences, 2008 - Elsevier
… of NPCs on T cell activation and proliferation in lymph nodes. In conclusion, neural precursor
cells exert an immunomodulatory effect that inhibits CNS inflammation. Cell therapy in MS …

[HTML][HTML] Mesenchymal stem cells: emerging mechanisms of immunomodulation and therapy

JD Glenn, KA Whartenby - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
… Effects of cytokine milieu on mesenchymal stem cell immune-modulation. Mesenchymal stem
cell (MSC) modulation of immune responses is strongly affected by the makeup of cytokine …

Mesenchymal stem cells: mechanisms of immunomodulation and homing

H Yagi, A Soto-Gutierrez, B Parekkadan… - Cell …, 2010 - journals.sagepub.com
cells, also referred to as mesenchymal stem cells (MSCs), are known to be the precursor
cells for … MSCs are anchorage-dependent cells, as opposed to other cells from bone marrow …

Mesenchymal stem cells: immunobiology and role in immunomodulation and tissue regeneration

JA Kode, S Mukherjee, MV Joglekar, AA Hardikar - Cytotherapy, 2009 - Elsevier
… of progenitors for cell replacement therapy. Their immunomodulatory properties have raised
… These facts are strongly reflected in the current exponential growth in stem cell research in …

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

Y Wang, X Chen, W Cao, Y Shi - Nature immunology, 2014 - nature.com
… contain not only specific unipotent stem cells, such as skeletal muscle stem cells and … stem
cells, but also multipotent stem cells, such as neural stem cells and hematopoietic stem cells 6 …