Stem cell therapy for COVID‐19, ARDS and pulmonary fibrosis

Z Li, S Niu, B Guo, T Gao, L Wang, Y Wang… - Cell …, 2020 - Wiley Online Library
… to a mild cytokine storm, missing the optimal detection time window and limited analysis of
inflammation indices, these results serve as a reminder that stem cell clinical trials should be …

[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… For the prevention and treatment of cytokine storm and possible lung fibrosis after COVID-19
pneumonia, mesenchymal stem cells (MSCs)-based immunomodulation treatment has …

Cytokine storm in COVID-19 and other diseases: emerging therapeutic interventions

S Sahu, R Dharra, M Gun, S Datta, AK Akela, A Kumar - Stem Cells, 2024 - Elsevier
cell type, differentiation stage, activation stage, and the nature of the stimuli [4]. The coordinated
production of cytokines … of proinflammatory cytokines, often termed as cytokine storm (CS…

[HTML][HTML] Review of trials currently testing stem cells for treatment of respiratory diseases: facts known to date and possible applications to COVID-19

F Majolo, GL da Silva, L Vieira, LFSM Timmers… - Stem cell reviews and …, 2021 - Springer
… Basically, the ongoing studies on coronavirus are using mesenchymal stem cells (MSCs) …
is the cytokine storm, however MSCs can prevent or mitigate this cytokine storm through their …

Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies.

H Reihani, A Sedaghat, AA Moghadam… - Regenerative …, 2021 - europepmc.org
storm” process. This process can cause injury to … cytokine storm, but the safety and
effectiveness of each of them are still in doubt. Mesenchymal stem cells (MSCs) are multipotent cells

[HTML][HTML] Updates on clinical trials evaluating the regenerative potential of allogenic mesenchymal stem cells in COVID-19

D Sharma, F Zhao - NPJ Regenerative medicine, 2021 - nature.com
… Uncontrolled cytokine production and the lack of substantive … involving the infusion of
mesenchymal stem cells (MSCs) due … cytokines that may drive COVID-19 associated cytokine

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
cellular components of the immune response corroborating with changes in cytokine levels
while discussing cytokine … brief potential therapies attempting to modulate the cytokine storm. …

[HTML][HTML] Immunomodulatory effect of mesenchymal stem cells and mesenchymal stem-cell-derived exosomes for COVID-19 treatmen

K Jayaramayya, I Mahalaxmi, MD Subramaniam… - BMB …, 2020 - ncbi.nlm.nih.gov
… it is the cytokine storm in COVID-19 that leads to acute respiratory distress syndrome (ARDS)
(3). The cytokine storm in COVID-19 refers to the fact that a variety of cytokines are rapidly …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… Mesenchymal stem cells (MSC) possess potent immunomodulatory activities [47]. Several
… trials testing the application of mesenchymal stromal stem cells (SC) (NCT04361942 and …

[HTML][HTML] Mesenchymal stem cell-based therapy and exosomes in COVID-19: current trends and prospects

M Abdelgawad, NS Bakry, AA Farghali… - Stem cell research & …, 2021 - Springer
… The virus causes an exaggerated immune response, resulting in a cytokine storm and
acute … response or cytokine storm associated with COVID-19. Mesenchymal stem cells (MSCs), …