Regulation of inflammatory cytokine storms by mesenchymal stem cells

L Wang, Y Li, M Xu, Z Deng, Y Zhao, M Yang… - Frontiers in …, 2021 - frontiersin.org
… both the cellular and molecular levels, and described the anti-inflammatory mechanisms
and related molecular pathways. Finally, we review the safety and efficacy of stem cell therapy …

Cytokine storm in COVID-19: An overview, mechanism, treatment strategies, and stem cell therapy perspective

NU Azmi, MU Puteri, D Lukmanto - … Sciences and Research, 2020 - scholarhub.ui.ac.id
… Therefore, controlling or suppressing the cytokine storm in COVID-19 becomes one of …
cytokine storm, and current and stem cell-based treatment strategies to inhibit the cytokine storm

[HTML][HTML] Fostering mesenchymal stem cell therapy to halt cytokine storm in COVID-19

M Jeyaraman, A John, S Koshy, R Ranjan… - … et Biophysica Acta (BBA …, 2021 - Elsevier
… Furthermore, MSCs attenuate the cytokine storm induced by pro-inflammatory cytokines,
restrict mononuclear entry into alveolar cells, and clear the alveolar oedematous fluid as shown …

[HTML][HTML] Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies

NK Farkhad, H Reihani, AA Moghadam… - Regenerative …, 2021 - Elsevier
… mesenchymal Stem Cells (AT-MSCs) significantly reduced IL-6 which … inflammatory cytokines
involved in the cytokine storm … -inflammatory cytokine (IL-10) and decrease in inflammatory

Mesenchymal stem cell immunomodulation: In pursuit of controlling COVID-19 related cytokine storm

N Song, H Wakimoto, F Rossignoli, D Bhere… - Stem Cells, 2021 - academic.oup.com
… -19, could elicit a cytokine storm that drives edema, dysfunction … stem cells (MSCs), owing
to their powerful immunomodulatory abilities, have the potential to attenuate the cytokine storm

SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine storm” and risk factor for damage of hematopoietic stem cells

MZ Ratajczak, M Kucia - Leukemia, 2020 - nature.com
… 1 may lead to Nlrp3 inflammasome overactivation, implying that the virus not only triggers
cytokine storm but most likely also affects the stem cell compartment in various organs and we …

The role of mesenchymal stromal cells in immune modulation of COVID-19: focus on cytokine storm

M Kavianpour, M Saleh, J Verdi - Stem Cell Research & Therapy, 2020 - Springer
… Immunomodulation effect of mesenchymal stem cells on cytokines storm led by COVID-…
cells to infection areas and localizes inflammation. The lethal unchecked systemic inflammatory

Ascorbic acid and IFNγ preconditioning enhance the potency of human mesenchymal stem cells to ameliorate LPS induced cytokine storm

A Sanap, S Kheur, A Kharat, R Bhonde - International …, 2023 - Elsevier
… The mesenchymal Stem Cells (MSCs) is one of the leading contender in therapeutic
management of cytokine storm implicated in the COVID-19 and other inflammatory conditions. This …

[HTML][HTML] Mesenchymal stem cells as living anti-inflammatory therapy for COVID-19 related acute respiratory distress syndrome

F Lin, TE Ichim, S Pingle, LD Jones… - … journal of stem cells, 2020 - ncbi.nlm.nih.gov
… In this review, we discuss the immunomodulatory effects of stem cells and the role of
MSCs as potential therapeutic options for cytokine storm and/or ARDS in COVID-19. …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
cytokine storms, such as inhibition of cytokines, corticosteroids, blood purification therapy, and
mesenchymal stem cell … advances in the research of cytokine storms induced by COVID-19…