[HTML][HTML] Structural basis of receptor recognition by SARS-CoV-2

J Shang, G Ye, K Shi, Y Wan, C Luo, H Aihara, Q Geng… - Nature, 2020 - nature.com
… the structural basis of ACE2 recognition by SARS-CoV-2, we aimed to crystallize the
SARS-CoV-2 … Our strategy was informed by previous crystallization of the SARS-CoV RBD–ACE2 …

[HTML][HTML] Structural basis of SARS-CoV-2 and SARS-CoV antibody interactions

E Gavor, YK Choong, SY Er, H Sivaraman… - Trends in …, 2020 - cell.com
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV, and discuss …
rampant SARS-CoV-2 infections. We provide a perspective on the mechanisms of SARS-CoV-2-…

[HTML][HTML] Structural basis of potential inhibitors targeting SARS-CoV-2 main protease

HM Mengist, T Dilnessa, T Jin - Frontiers in Chemistry, 2021 - frontiersin.org
… severe acute respiratory syndrome Coronavirus -2 (SARS-CoV-2) … structure-based improved
drugs. This review discusses the structural basis of potential inhibitors targeting SARS-CoV-…

Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex

Y Ma, L Wu, N Shaw, Y Gao, J Wang… - Proceedings of the …, 2015 - National Acad Sciences
… The molecular basis of both these functions is unknown. Here, we describe crystal structures
of severe acute respiratory syndrome (SARS)-CoV nsp14 in complex with its activator …

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

R Yan, Y Zhang, Y Li, L Xia, Y Guo, Q Zhou - Science, 2020 - science.org
structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. This confirms
that the novel virus SARS-CoV-… 2 (ACE2) as a receptor similar to SARS-CoV. Zhou et al …

Structural basis of a shared antibody response to SARS-CoV-2

M Yuan, H Liu, NC Wu, CCD Lee, X Zhu, F Zhao… - Science, 2020 - science.org
… to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine
design and drug discovery. We analyzed 294 anti–SARS-CoV-2 antibodies and found that …

Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement

M McCallum, N Czudnochowski, LE Rosen, SK Zepeda… - Science, 2022 - science.org
… This work defines the molecular basis for the broad evasion of humoral immunity exhibited
by SARS-CoV-2 Omicron and underscores the SARS-CoV-2 S mutational plasticity as well as …

[PDF][PDF] Structural basis for RNA replication by the SARS-CoV-2 polymerase

Q Wang, J Wu, H Wang, Y Gao, Q Liu, A Mu, W Ji… - Cell, 2020 - cell.com
… molecular basis of SARS-CoV-2 RNA replication by determining the cryo-EM structures of
… Compared with the apo complex, the structures show notable structural rearrangements …

[HTML][HTML] Structural basis of RNA cap modification by SARS-CoV-2

T Viswanathan, S Arya, SH Chan, S Qi, N Dai… - Nature …, 2020 - nature.com
… -resolution structure of a ternary complex of SARS-CoV-2 … sugar of the first nucleotide of
SARS-CoV-2 mRNA. We observe … (25 Å) ligand-binding site unique to SARS-CoV-2, which can …

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2

M Thoms, R Buschauer, M Ameismeier, L Koepke… - Science, 2020 - science.org
… 3×FLAG-tagged Nsp1 of SARS-CoV-2 and SARS-CoV and their respective mutants in …
In summary, Nsp1 from both SARS-CoV and SARS-CoV-2 binds 40S and 80S ribosomes …