Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

X Luan, B Chen, W Shang, W Yin, Y Jin… - Acta Pharmacologica …, 2023 - nature.com
… To determine the structural basis of SARS-COV-2 M pro inhibition by … structure of GC376
bound SARS-COV-2 M pro at the resolution of 2.35 Å. Like SARS-CoV M pro , the SARS-CoV-2 …

Structural insights into SARS-CoV-2 proteins

R Arya, S Kumari, B Pandey, H Mistry, SC Bihani… - Journal of molecular …, 2021 - Elsevier
structures of SARS-CoV-2 proteins in the last few months. These include structures of
viral non-structural, structural, … , we discuss important structural features of different SARS-CoV-2 …

Structural basis for accommodation of emerging B. 1.351 and B. 1.1. 7 variants by two potent SARS-CoV-2 neutralizing antibodies

G Cerutti, M Rapp, Y Guo, F Bahna, J Bimela… - Structure, 2021 - cell.com
Structural basis of antibody 2–7 accommodation of mutation N501Y in emerging strains
Cryo-EM analysis of the Fab from antibody 2–7 in complex with SARS-CoV-… 2Structural basis of …

Structural basis of fitness of emerging SARS-COV-2 variants and considerations for screening, testing and surveillance strategy to contain their threat

SR Islam, D Prusty, SK Manna - MedRxiv, 2021 - medrxiv.org
… mutations have been detected in SARS-COV-2, which were … Thus, in this study, we analyze
the structural basis of most … -temporal trend of evolution SARS-COV-2 mutants of concern to …

Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s

L Li, P Han, B Huang, Y Xie, W Li, D Zhang, P Han… - Cell Discovery, 2022 - nature.com
… at the binding interface of the SARS-CoV-2 RBD and human … structural basis and host
range of this variant have been conducted 20 . In addition to the crystal and cryo-EM structures

SARS-CoV-2: structure, biology, and structure-based therapeutics development

MY Wang, R Zhao, LJ Gao, XF Gao… - Frontiers in cellular …, 2020 - frontiersin.org
… 14-base RNA in the template strand as well as 11-base RNA in … are base-stacking interactions
between RMP and the base of … between RMP and the uridine base of the template strand. …

SARSCoV‐2, the pandemic coronavirus: Molecular and structural insights

SB Kadam, GS Sukhramani, P Bishnoi… - Journal of basic …, 2021 - Wiley Online Library
… Moreover, the crystal structures of SARS-CoV-2 proteins with … aspects of SARS-CoV-2
including secondary structures in the … the aggressive spread of the SARS-CoV-2. The mutations …

[HTML][HTML] Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2

L Tang, D Zhang, P Han, X Kang, A Zheng… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
… Complex structure of SARS-CoV-2 RBD with bACE2-Ra … investigate the molecular basis
of the interaction between bACE2-Ra and SARS-CoV-2 RBD, we prepared SARS-CoV-2 RBD …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … (BBA)-Molecular Basis …, 2020 - Elsevier
… protein regions of the SARS-CoV-2 polyprotein that may be useful to understand the structural
basis of infection, structure-based drug discovery and interaction of SARS-CoV-2 proteins …

Update on the target structures of SARS-CoV-2: A systematic review

M Prajapat, P Sarma, N Shekhar… - Indian Journal of …, 2020 - journals.lww.com
… In the systematic review, we systematically reviewed the structural basis of different target
proteins of SARS-corona virus (CoV2) from a viral life cycle and from drug design perspective. …