Structure and function of major SARS-CoV-2 and SARS-CoV proteins

R Gorkhali, P Koirala, S Rijal… - … and biology insights, 2021 - journals.sagepub.com
… residue on the edge of nitrogenous base recognizing the hydrophobic pocket in SARS-CoV-2-N-…
in nonpolar properties in the nitrogenous base-binding site of SARS-CoV-2-N-NTD. …

[HTML][HTML] Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein

P Chaurasia, THO Nguyen, LC Rowntree… - Journal of Biological …, 2021 - ASBMB
… -reactivity toward analogous peptides from existing SARS-CoV-2 variants and closely related
… Overall, we defined the structural basis underpinning biased TCR recognition of CD8 + T …

Structural basis for the recognition of the 2019-nCoV by human ACE2

R Yan, Y Zhang, Y Guo, L Xia, Q Zhou - BioRxiv, 2020 - biorxiv.org
… Our structure provides the molecular basis for computational and … Structural elucidation
nCoV-RBD to ACE2 also set up the … methods and potential therapeutics against the 2019-nCoV. …

[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
… These non-structural, structural and accessory proteins … SARS-CoV-2 proteins can individually
perform essential … In this Review, we delineate the structural features of SARS-CoV-2 from …

[HTML][HTML] Structural basis of mercury-and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors

CC Lee, CJ Kuo, MF Hsu, PH Liang, JM Fang, JJ Shie… - FEBS letters, 2007 - Elsevier
… In this study, five crystal structures allow us to identify ligand binding regions of metal-conjugated
compounds as inhibitors of SARS-CoV 3CL pro . The 3CL pro -PMA structure reveals …

Structural basis of white-tailed deer, Odocoileus virginianus, ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity

P Han, Y Meng, D Zhang, Z Xu, Z Li, X Pan… - Journal of …, 2023 - Am Soc Microbiol
… the United States were detected as SARS-CoV-2 positive by RT-PCR, and SARS-CoV-2-binding …
The structural basis of WTD ACE2 binding to RBDs from different SARS-CoV-2 variants …

Basic virology of SARS-CoV 2

V Ravi, S Saxena, PS Panda - Indian journal of medical microbiology, 2022 - Elsevier
SARS CoV 2 infection [31]. Involvement of cardiovascular system is reflected by release of
highly sensitive troponin and natriuretic peptides [32]. Cytokines normally regulating immunity…

[HTML][HTML] Structure and function of SARS-CoV-2 polymerase

HS Hillen - Current opinion in virology, 2021 - Elsevier
… These studies provided the structural basis for remdesivir incorporation into the product
RNA and show that the polymerase can add further nucleotides to the nascent chain by …

[PDF][PDF] Molecular structure, pathogenesis and virology of SARS-CoV-2: A review

A Akram, N Mannan - Bangladesh Journal of Infectious …, 2020 - pdfs.semanticscholar.org
… Therefore, on the basis of these, it seems likely that the 2019-nCoV … Recently, CoV sequences
closely related to SARSCoV-2 … Pangolin SARSlike CoVs (Pan_SL-CoV) form two distinct …

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

NH Moeller, K Shi, Ö Demir, C Belica… - Proceedings of the …, 2022 - National Acad Sciences
… 1.6-Å resolution crystal structure of severe acute respiratory syndrome CoV 2 (SARS-CoV-2) …
To better understand the basis of the strong preference for RNA over DNA substrate above, …