… efforts have been made to get structural insights on NDM-1, … structures were available in
the Protein Data Bank (PDB), 22 of them in the apo form and the remaining 28 complexed with β-…

… Additionally, product complex structures of hydrolyzed benzylpenicillin-, methicillin-, … structural
data for any metallo-β-lactamase reported to date. Finally, we present the crystal structure …

… differences from the holo structure, some inhibitors were shown to … This structural information
could prove essential in the … and metallo-β-lactamases, one of the main steps in structure-…

… In the study, we selected the MBL bound to hydrolysed Meropenem as a target protein to
understand the structural insights of MBL natural inhibitors. This comparative study between …

A novel subclass B3 metallo-β-lactamase (MBL), SMB-1, recently identified from a Serratia
marcescens clinical isolate, showed a higher hydrolytic activity against a wide range of β-…

… , we solved 1.4 to 1.6 Å crystal structures of SMB-1 (S erratia metallo-β-lactamase 1), a …
In these structures, SMB-1 interacts mainly with the carbapenem core structure via elements …

… the crystal structure of NDM and … , β-sheet and loop structures of NDM enzyme, having
different mutations occurred in these regions. The effect of these substitutions on its structure and …

… structure-based substrate specificity of MBLs. Herein, we compared several tens of B1, B2,
and B3 MBLs in sequence and structure and proposed structural insights … chemical structures …

… and hydrolysis mechanism by β-lactamases. The structural insight into various β-lactams will
… in multidrug-resistant bacteria and help to develop better β-lactam antibiotics and inhibitors. …

… The large diversity of active-site structures and metal content … Here, we report the crystal
structure of the periplasmic di-Zn(II… as a duplication of two structurally similar α/β hemidomains. …