Subcutaneous REGEN-COV antibody combination to prevent Covid-19

MP O'Brien, E Forleo-Neto, BJ Musser… - … England Journal of …, 2021 - Mass Medical Soc
REGEN-COV program, we hypothesized that a combination of neutralizing, noncompeting
monoclonal antibodies could have activity in both treatment and prevention of SARS-CoV-2 …

[HTML][HTML] Subcutaneous REGEN-COV antibody combination in early asymptomatic SARS-Cov-2 infection: a randomized clinical trial

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… of symptoms with subcutaneous REGEN-COV for participants … no participants receiving
subcutaneous REGEN-COV had these … REGEN-COV. Overall, these results demonstrate that …

[PDF][PDF] Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 [published online ahead of print, 2021 Aug 4]

MP O'Brien, E Forleo-Neto… - N Engl J …, 2021 - jaykolasinac.commons.gc.cuny.edu
… (previously known as REGN-COV2), a combination of the monoclonal antibodies
subcutaneous REGEN-COV prevents severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Subcutaneous REGEN-COV antibody administration in a community pharmacy

TS Dougherty, J McBride, CL Barnett… - Journal of the American …, 2023 - Elsevier
… The objective of this study was to describe an innovative service and evaluate the safety
of administering REGEN-COV, a monoclonal antibody combination of casirivimab and …

Effect of subcutaneous casirivimab and imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early asymptomatic SARS-CoV-2 …

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
… the SARS-CoV-2 spike protein receptor–binding domain and block virus entry. The 2-antibody
combination reduces the risk of emergence of treatment-induced SARS-CoV-2 variants …

Phase 2 dose-ranging study of the virologic efficacy and safety of the combination COVID-19 antibodies casirivimab and imdevimab in the outpatient setting

C Portal-Celhay, E Forleo-Neto, W Eagan, BJ Musser… - medRxiv, 2021 - medrxiv.org
… characterisation of the clinical effects of REGEN-COV. Moreover, identifying a … of REGEN-COV
in the setting of a global pandemic. A 1200 mg subcutaneous (SC) dose of REGEN-COV

Breakthrough omicron COVID-19 infections in patients receiving the REGEN-Cov antibody combination

A Flahault, J Touchard, H Péré, L Ulrich… - Kidney …, 2022 - kidney-international.org
… Green dashed line: cumulative number of REGEN-Cov administrations. Red line: cumulative
number of COVID-19 infections among patients treated with REGEN-Cov in our cohort. …

Compassionate Use of REGEN-COV® in Patients With Coronavirus Disease 2019 (COVID-19) and Immunodeficiency-Associated Antibody Disorders

D Stein, E Oviedo-Orta, WA Kampman… - Clinical Infectious …, 2022 - academic.oup.com
… In this retrospective analysis of immunodeficient patients granted REGEN-COV under
emergency compassionate use, REGEN-COV treatment was associated with rapid viral clearance …

COVID-19 prevention with subcutaneous administration of the monoclonal antibodies casirivimab and imdevimab: Subgroup analysis in participants with …

MP O'Brien, E Forleo-Neto, BJ Musser, F Isa… - American Heart …, 2021 - Elsevier
antibody combination casirivimab and imdevimab (REGEN-COVTM) administered
subcutaneously (SC) prevented symptomatic SARS-CoV-… same household as a SARS-CoV-2-infected …

Effectiveness of REGEN-COV antibody combination in preventing severe COVID-19 outcomes

S Hayek, Y Ben-Shlomo, N Dagan, BY Reis… - Nature …, 2022 - nature.com
REGEN-COV, a combination of the monoclonal antibodies casirivimab and imdevimab, has
been approved as a treatment for high-risk patients infected with SARS-CoV… of REGEN-COV