Cytokine storm and use of anakinra in a patient with COVID-19

P Nemchand, H Tahir, R Mediwake… - BMJ Case Reports …, 2020 - casereports.bmj.com
… We suggest that earlier identification of patients developing cytokine storm and COVID-19
infection with monitoring of biomarkers (rising ferritin, CRP) and treatment with IL-1R …

Pharmaco-immunomodulatory interventions for averting cytokine storm-linked disease severity in SARS-CoV-2 infection

A Kumar, A Sharma, NV Tirpude, S Sharma… - …, 2022 - Springer
patients treated with cytokine inhibitors and 103 patients treated with standard of care.
Treatment resulted in a significantly greater survival rate compared to standard therapy in patients

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
… of patients with COVID-19 infection and save the patients' … cytokine storm and the options
to inhibit the cytokine storm, in … has significantly improved survival in patients with sepsis. Anti-…

[HTML][HTML] Individualized High Dose Intravenous Anakinra Treatment in Cancer Patients with COVID-19 Associated Cytokine Storm: A Retrospective Controlled Study

R Çakmak, M Bektaş - Infectious Diseases & Clinical Microbiology, 2024 - ncbi.nlm.nih.gov
… In survival analysis, a significantly lower survival rate … in patients receiving SoC compared
to anakinra. Our study indicates that cytokine storm is the leading cause of mortality in patients

The looming storm: blood and cytokines in COVID-19

S Kaur, R Bansal, S Kollimuttathuillam, AM Gowda… - Blood reviews, 2021 - Elsevier
… products as well as cytokines such as IL-6 are emerging as … abnormalities including
cytokine storm, hypercoagulable … drugs targeting cytokine storm in patients with SARS-CoV-2. …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
… Under inflammatory cytokine storm, the dark gray circles refer to proinflammatory cytokines
and … This review will focus on the inflammatory cytokine storm and its implications on human …

[PDF][PDF] Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome

LA Monteagudo, A Boothby… - ACR open rheumatology, 2020 - Wiley Online Library
… improvement in adult patients with MAS . This method for treating cytokine storm should be
… in the subgroup of patients with severe disease who have a cytokine storm presentation. …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… severe hyperinflammatory state or cytokine storm (CS) for … Although the individual components
of CS are varied, IL-6 … in recent retrospective studies of patient survival in COVID-19. …

[HTML][HTML] Role of therapeutic plasma exchange in the management of COVID-19-induced cytokine storm syndrome

M Beraud, S Al Hashami, M Lozano, A Bah… - … and Apheresis Science, 2022 - Elsevier
… to as cytokine storm syndrome (CSS). Management of critically ill patients with COVID-19 …
approach to eliminate inflammatory factors and cytokines, offset the pathologic coagulopathy…

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… in cytokine levels while discussing cytokine sources and biological functions. Finally, we
discuss in brief potential therapies attempting to modulate the cytokine storm. … and survival. …