… cell adhesion, neurodevelopment, and synaptic biology in bipolar disorder along with … loci
include a number of genes that code for genes involved in neurodevelopment, synaptic biology…

… Because of the clear synaptic signal, … biological processes implicated by common and
ultra-rare genetic variation and that URVs can be leveraged to prioritize genes within GWAS loci. …

… Downstream analyses of these novel loci highlight synaptic function, in contrast to common
AD-associated variants, which implicate innate immunity and amyloid processing. These loci …

… synaptic functioning, are also associated with an increased risk of SCZ. Thus, miR137 represents
an attractive target aimed at correcting the molecular basis for synaptic … synaptic protein …

… biological network of genes affected by rare de novo CNVs in autism. The genes forming the
network are primarily related to synapse … autistic children contained 47 loci in total affecting …

… After determining the correlating and anti-correlating neighbors of genes in the 108 loci we
… significant biological process associated with this gene set is again “synaptic transmission”. …

… yielded 287 distinct genomic loci significantly associated with schizophrenia, each … on
synaptic biology and synaptic pruning. A synaptic pruning hypothesis of schizophrenia posits that …

… Overall, identification of shared biological mechanisms … by also scrutinizing overlap in genomic
loci, SNPs, genes, gene … has synaptic annotations and whether any synaptic processes or …

… vivo results in defects in synapse development and behavior, … Although both genetic and
molecular biological approaches … To address this, we analyzed MeCP2 binding at multiple loci …

… We performed MEF2D ChIP-chip using a custom tiling microarray containing the genomic
loci of the 182 genes identified in our mRNA profiling experiments (including 10 kb 5′ and 3…