Plant synthetic biology for molecular engineering of signalling and development

JL Nemhauser, KU Torii - Nature plants, 2016 - nature.com
… Here, we provide a brief history of plant synthetic biology and … 1 , plant biology has been
at the forefront of developing tools to … genome to cellular signalling architecture to forecasting …

Synthetic biology: lessons from engineering yeast MAPK signalling pathways

K Furukawa, S Hohmann - Molecular microbiology, 2013 - Wiley Online Library
signalling components individually. Engineering signalling pathways with concepts of synthetic
biology … existing systems and enables generating signalling behaviours useful for future …

Using synthetic biology to explore principles of development

J Davies - Development, 2017 - journals.biologists.com
… that synthetic biology allows us to test and further develop high-level principles of biological
self-… and engineered degradation signals are much more relevant to the practice of synthetic

Biological signal generators: integrating synthetic biology tools and in silico control

TD Scott, K Sweeney, MN McClean - Current opinion in systems biology, 2019 - Elsevier
biological signal generators. Here, we review recent advances in biological signal
generator construction and their use in systems biology studies. Challenges for constructing …

Synthetic biology of cell signaling

J Hansen, Y Benenson - Natural Computing, 2016 - Springer
… in synthetic signaling pathways and synthetic regulatory mechanisms. The mechanisms of
cellular signaling pathways vary, but they have in common signal … with signal propagation …

Synthetic biology: applications come of age

AS Khalil, JJ Collins - Nature Reviews Genetics, 2010 - nature.com
Synthetic biology is bringing together engineers and biologists to design and build novel …
The de novo engineering of genetic circuits, biological modules and synthetic pathways is …

Synthetic biology—the synthesis of biology

S Ausländer, D Ausländer… - Angewandte Chemie …, 2017 - Wiley Online Library
… One class of such useful parts is gene switches, which are capable of sensing a signal and
… to the signal, but have instead been engineered to directly report on the signal through …

Synthetic biology: understanding biological design from synthetic circuits

S Mukherji, A Van Oudenaarden - Nature Reviews Genetics, 2009 - nature.com
… In this light, synthetic circuits have been crucial as simplified test beds in which … synthetic
biology to the generation of increasingly quantitative descriptions of gene expression and signal

Novel synthetic biology approaches for developmental systems

C Ho, L Morsut - Stem Cell Reports, 2021 - cell.com
… areas where synthetic biology tools are used in top-down and bottom-up approaches for
studying and constructing developmental systems. First, we discuss how synthetic biology tools …

Engineering living therapeutics with synthetic biology

A Cubillos-Ruiz, T Guo, A Sokolovska… - Nature Reviews Drug …, 2021 - nature.com
… that have used synthetic biology approaches to programme cellular behaviours. We
focus on efforts that involve the biological sensing and computation of signals derived from …