Blood-brain barrier: more contributor to disruption of central nervous system homeostasis than victim in neurological disorders

M Xiao, ZJ Xiao, B Yang, Z Lan, F Fang - Frontiers in Neuroscience, 2020 - frontiersin.org
cerebral microvascular system. It plays a pivotal role in maintaining central nervous system
(CNS) homeostasis … between the circulation and the brain and protects the neural tissue from …

[HTML][HTML] The blood-brain barrier in brain homeostasis and neurological diseases

N Weiss, F Miller, S Cazaubon, PO Couraud - Biochimica et Biophysica …, 2009 - Elsevier
barriers constituted by a variety of epithelia and in brain endothelium forming … blood-brain-barrier
(BBB) which controls cerebral homeostasis and provides the central nervous system (…

[HTML][HTML] Bloodbrain barrier dynamics to maintain brain homeostasis

M Segarra, MR Aburto, A Acker-Palmer - Trends in neurosciences, 2021 - cell.com
… parenchyma, and it is an essential functional gatekeeper for the central nervous system (…
of BBB tightness to maintain brain homeostasis in response to extrinsic environmental factors …

Endothelial β-catenin signaling is required for maintaining adult bloodbrain barrier integrity and central nervous system homeostasis

KA Tran, X Zhang, D Predescu, X Huang… - Circulation, 2016 - Am Heart Assoc
… The bloodbrain barrier (BBB) formed by brain endothelial cells interconnected by tight
junctions is essential for the homeostasis of the central nervous system. Although studies have …

The dynamic bloodbrain barrier

J Keaney, M Campbell - The FEBS journal, 2015 - Wiley Online Library
… along the blood vessels of the central nervous system (CNS), the bloodbrain barrier (BBB) …
To conclude, as we increase our understanding of BBB involvement in brain homeostasis

The bloodbrain barrier—gatekeeper to neuronal homeostasis: clinical implications in the setting of stroke

K Schoknecht, Y David, U Heinemann - Seminars in cell & developmental …, 2015 - Elsevier
system to the peripheral immune system. As an important player in brain homeostasis,
bloodbrain barrier … of many brain diseases including stroke, traumatic brain injury, brain tumors, …

Dual role of ALCAM in neuroinflammation and bloodbrain barrier homeostasis

MA Lécuyer, O Saint-Laurent… - Proceedings of the …, 2017 - National Acad Sciences
… In the current study, we now provide in vivo evidence that genetic neutralization of ALCAM
does not affect the peripheral immune system homeostasis nor T-cell proliferation in mouse. …

[HTML][HTML] Blood brain barrier: the role of calcium homeostasis

A Yarlagadda, S Kaushik, AH Clayton - Psychiatry (Edgmont), 2007 - ncbi.nlm.nih.gov
… and intracellular compartments of the central nervous system, involving processes that
include transport mechanisms across the blood brain barrier (BBB) and cellular membranes, …

Regulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseases

W Zheng, AD Monnot - Pharmacology & therapeutics, 2012 - Elsevier
brain barrier system in maintaining Fe and Cu homeostasis in the CNS and the relationship
between distorted brain Fe … characteristics of the brain barrier system are first introduced. The …

A hidden epithelial barrier in the brain with a central role in regulating brain homeostasis. Implications for aging

R E. Vandenbroucke - Annals of the American Thoracic Society, 2016 - atsjournals.org
… Consequently, advanced knowledge of the choroid plexus–cerebrospinal fluid system in
aging is essential to better understand age-associated neurological diseases and might open …