Direct oral anticoagulants: evidence and unresolved issues

N Chan, M Sobieraj-Teague, JW Eikelboom - The Lancet, 2020 - thelancet.com
… paper, we review the pharmacology of direct oral anticoagulants, … perspectives for the
development of oral anticoagulants. … thromboembolism: a systematic review and meta-analysis. …

Safety of treatment with oral anticoagulants in the elderly: a systematic review

BA Hutten, AWA Lensing, RA Kraaijenhagen, MH Prins - Drugs & aging, 1999 - Springer
… The anticoagulant effects of oral anticoagulants not only vary markedly among individuals
but … This systematic review was performed to document the incidence of oral anticoagulant-…

The new oral anticoagulants

D Garcia, E Libby, MA Crowther - Blood, The Journal of the …, 2010 - ashpublications.org
… Although their first application in clinical practice occurred in the 1940s, vitamin K
antagonists remain the only form of oral anticoagulant medication approved for long-term use. …

Direct oral anticoagulants in the treatment of acute venous thromboembolism: a systematic review and meta-analysis

A Gómez-Outes, AI Terleira-Fernández… - Thrombosis research, 2014 - Elsevier
… We systematically reviewed and meta-analysed clinical outcomes with direct oral anticoagulants
(DOAC: dabigatran, rivaroxaban, apixaban or edoxaban) for treatment of acute VTE. …

Laboratory assessment of the anticoagulant activity of direct oral anticoagulants: a systematic review

BT Samuelson, A Cuker, DM Siegal, M Crowther… - Chest, 2017 - Elsevier
… We performed a systematic review of the literature to examine use of coagulation assays
for assessment of the anticoagulant activity of DOACs. A search of PubMed, Web of Science, …

Perioperative management of patients receiving oral anticoagulants: a systematic review

AS Dunn, AGG Turpie - Archives of internal medicine, 2003 - jamanetwork.com
… -weight heparin (LMWH) while oral anticoagulation is withheld can decrease the risk of …
To better inform clinicians on the available evidence, we performed a systematic review and …

Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature

F Dentali, N Riva, M Crowther, AGG Turpie, GYH Lip… - Circulation, 2012 - Am Heart Assoc
… of a third reviewer (WA) if necessary. Studies were considered potentially eligible for this
systematic review if they met … Twelve studies were therefore included in this systematic review. …

Overview of the new oral anticoagulants: opportunities and challenges

CH Yeh, K Hogg, JI Weitz - Arteriosclerosis, thrombosis, and …, 2015 - Am Heart Assoc
… Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists
in the treatment of acute symptomatic venous thromboembolism: a systematic review and …

Pros and cons of new oral anticoagulants

KA Bauer - Hematology 2013, the American Society of …, 2013 - ashpublications.org
… For more than 50 years, vitamin K antagonists (eg, warfarin) were the only available oral
anticoagulants. It has now been 3 years since the first of the new oral anticoagulants (NOACs), …

Underuse of oral anticoagulants in atrial fibrillation: a systematic review

IM Ogilvie, N Newton, SA Welner, W Cowell… - The American journal of …, 2010 - Elsevier
… Despite an efficacious oral anticoagulation therapy (warfarin), atrial fibrillation patients at
high risk for stroke are often under-treated. This systematic review compares current treatment …