Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways

C Pan, L Lou, Y Huo, G Singh, M Chen… - Therapeutic …, 2011 - journals.sagepub.com
… Amino acid depleted human umbilical vein endothelial cells (HUVECs) when incubated with
different concentrations of Salvianolic acid B (Sal B) or Tanshinone IIA (Tan IIA) for 3 hours …

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro

JP Dai, DX Zhu, JT Sheng, XX Chen, WZ Li, GF Wang… - Molecules, 2015 - mdpi.com
… In this study, we have investigated the effect and mechanism of tanshinone IIA1 (Tan-IIA1),
salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important active compounds of …

Anti-allergic effects of salvianolic acid A and tanshinone IIA from Salvia miltiorrhiza determined using in vivo and in vitro experiments

JY Heo, DS Im - International Immunopharmacology, 2019 - Elsevier
… of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects have been studied
[11]. Recently, salvianolic acid B … of salvianolic acid A, tanshinone I, and tanshinone IIA in …

Salvianolic acid B and tanshinone IIA synergistically improve early diabetic nephropathy through regulating PI3K/Akt/NF-κB signaling pathway

Z Xu, K Cai, SL Su, Y Zhu, F Liu, JA Duan - Journal of Ethnopharmacology, 2024 - Elsevier
salvianolic acid B and tanshinone IIA. We found that salvianolic acid B and tanshinone IIA
can … by salvianolic acid B, tanshinone IIA and their combinations to illustrate the benefits of …

Effects of salvianolic acid B and tanshinone IIA on the pharmacokinetics of losartan in rats by regulating the activities and expression of CYP3A4 and CYP2C9

R Wang, H Zhang, Y Wang, X Yu, Y Yuan - Journal of Ethnopharmacology, 2016 - Elsevier
… of CDST, tanshinone IIA (Tan IIA) and salvianolic acid B (SA-B) were chosen to investigate
the potential influences on the metabolism of LST. The structure of Tan IIA is shown in Fig. 1A, …

Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro …

D Elebeedy, WF Elkhatib, A Kandeil, A Ghanem… - RSC …, 2021 - pubs.rsc.org
… two promising compounds, tanshinone IIA (1) and carnosic acid (2). … and clinical studies
especially for tanshinone IIA (1) to be … acid (2), rosmarinic acid (3), and/or salvianolic acid (4). …

Simultaneous quantification of salvianolic acid B and tanshinone IIA of salvia tropolone tablets by UPLC-MRM-MS/MS for pharmacokinetic studies

JR Li, DX Li, L Li, WL Deng, LS Ding, HX Xu… - Acta …, 2014 - akjournals.com
… /mL for tanshinone IIA and 100 pg/mL−1 for salvianolic acid B… pg/mL for tanshinone IIA and
salvianolic acid B, respectively. … 85.9% for both tanshinone IIA and salvianolic acid B. The two …

[HTML][HTML] Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots

X Hao, Z Pu, G Cao, D You, Y Zhou, C Deng… - Journal of Advanced …, 2020 - Elsevier
… rich in bioactive tanshinone and salvianolic acid compounds. … Liposoluble tanshinones
and water-soluble phenolic acids … promotion of tanshinone and salvianolic acid biosynthesis …

Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats

Y Lu, X Liu, X Liang, L Xiang, W Zhang - Journal of Ethnopharmacology, 2011 - Elsevier
AIM OF THE STUDY: Tanshinone IIA (T), salvianolic acid B (S) and ginsenoside Rb1 (G) are
the three major active ingredients of Compound Danshen Formula (CDF) for its protective …

Pharmacological activity and mechanism of tanshinone IIA in related diseases

R Guo, L Li, J Su, S Li, SE Duncan, Z Liu… - Drug Design …, 2020 - Taylor & Francis
… and the hydrophilic component of Salvia miltiorrhiza (salvianolic acids) also play
important roles in the pharmacological activities of danshen in treating various diseases. The …