… Schematic figure shows the general concept of targeting epigenetic enzymes. In the middle,
an … The upper and lower figures show the induced change in gene expression by targeting a …

… Our lab has shown that STAT3 mediates EGF-induced expression of the repressor Twist
in epidermoid and mammary carcinoma cells [19]. We found STAT3 binding sites within the …

… , we also identified new cases of drug-induced expression regulation of drug targets. The
significant novel findings are the inhibitor-induced down-regulation of calmodulin 1, DNA …

… expression. We found a strong effect on serum-induced expression of the known SRF target
genes … could block the serum induced expression of target genes by indirectly blocking the …

… that now encompasses non-PPREs containing genes. It is also … PPAR expression and
activity, can itself have a significant influence on how the expression of subgroups of target genes …

… Targets of age-associated miRNAs are differentially expressed with age To examine if
expression of other target genes may be altered in older participants, we focused on previously …

… assay with expression levels of p53 target genes normalized … the basal expression level of
the five p53-target genes in p53… examined the expression of these five p53-target genes after …

… suppression of target genes, we profiled global expression of … We grouped genes that are
differentially expressed in wild-… all genes expressed in keratinocytes versus those targeted by …

… expression relationships among miRNA targets. We have developed a strategy based on
Co-expression Meta-analysis of miRNA Target genes (CoMeTa) to integrate expression data …

… induced expression of HRE-containing genes, we compared the level of VEGF in culture
supernatants of insulin-induced … stable transfection of an ARNT expression vector (Hoffman et al.…