… More than 800 million people suffer from kidney disease, yet the mechanism of … transcriptome
in 686 samples and single-cell open chromatin in 57,229 kidney cells. Heritability analysis …

… unmet need for biomarkers that reflect disease severity and the underlying molecular
mechanisms. We assessed transcriptome according to varying degrees of the SLEDAI-2K index.7 …

… Integrative analysis of somatic mutations and gene expression profiles was performed …
targetable mechanism in PBL subgroups. Our characterization of a mutational and transcriptomic …

… determine transcriptomic changes that not only deepen our insight into disease mechanisms,
… or altered pathways that might be targeted via currently available monoclonal antibodies or …

… transcriptional mechanisms underlying the differential expression of genes identified by
RNA-seq, we performed a transcription factor analysis using the Ingenuity Pathway Analysis …

… mechanisms of aberrant MAPK pathway activation in LCH, we performed WES, RNA-seq,
and targeted … In this study, genomic and transcriptomic analyses revealed novel BRAF …

… , but targetable mechanisms driving … mechanisms linking intratumor heterogeneity to tumor
evolution may reveal druggable dependencies. To do so, we use spatial transcriptomic and …

… scRNA-seq based transcriptome analyses in primary human tumors have not only revealed
… between T cell populations through integrating analysis of transcriptomes and T cell …

… Targeted therapy is critically under-utilized, and our understanding of mechanisms … To
address these deficiencies, we investigated the genomic and transcriptomic landscapes …

… These mechanisms have been targeted to prevent epileptogenesis in animal models. …
Furthermore, the analysis of transcriptomic data to identify common epileptogenic mechanisms in …