… Clinical studies suggest excessive release of inflammatory mediators leads to cytokinestorm, a … The review also portrays a question and debates: Can targetingcytokinestorm can be a …
Q Huang, X Wu, X Zheng, S Luo, S Xu… - Pharmacological Research, 2020 - Elsevier
… -inflammation and cytokinestorm highlights the necessity of early identification of cytokinestorm and implementation of anti-inflammatory treatment. Timely control of hyper-inflammatory …
N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
… Targeting various pro-inflammatorycytokines in a specific manner … cytokinestorm, and this review will summarize and discuss advances in targeted therapies against cytokinestorms …
… In this mini-review, we addressed the inflammatory pathways of the severe acute … host cytokinestorm. Furthermore, the proposed therapeutic options to reverse hyper-inflammation in …
RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
… to dampen the cytokinestorm syndrome to … cytokinestorm syndrome was targeting interleukin-6 (IL-6). Early during the pandemic, IL-6 concentrations were noted to be elevated, and IL-6…
BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
… clinical trials targetingcytokine production or effects failed. This review aims to summarize the pathophysiology of the cytokinestorm; to describe the type, effects, and kinetics of cytokine …
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - … transduction and targeted …, 2021 - nature.com
… , cytokinestorm (CS). The CS is characterized by hyperproduction of an array of pro-inflammatory cytokines … pro-inflammatorycytokines initiate different inflammatory signaling pathways …
D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
… ), which also stimulate inflammation resolution by promoting … anti-inflammatory processes, and preventing the cytokinestorm. … Targeting individual pro-inflammatorycytokines may not be …
J Liu, M Wan, CJ Lyon, TY Hu - Theranostics, 2020 - ncbi.nlm.nih.gov
… macrophage-targeted nanomedicines can be employed to attenuate cytokinestorms and … or other conditions associated with excessive pro-inflammatory responses. We also discuss …