COVID-19, immune system response, hyperinflammation and repurposingantirheumatic drugs

A Tufan, AA Güler… - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
… Several therapeutic agents have been developed inhibiting the cytokine itself, the signaling
… in COVID-19 patients [80]. Blockage of this growth factor may halt immunopathology caused …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - … and targeted therapy, 2020 - nature.com
… To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and therapeutic drugs. In this regard, treatments addressing the immunopathology of SARS-…

[HTML][HTML] COVID-19: The emerging immunopathological determinants for recovery or death

T Ahmad, R Chaudhuri, MC Joshi… - Frontiers in …, 2020 - frontiersin.org
… Nevertheless, these initial reports, along with the previous findings on SARS-CoV, are
the basis behind exploring the therapeutic efficacy of IFN treatment for COVID-19 patients. …

The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics

M Abbasifard, H Khorramdelazad - Life sciences, 2020 - Elsevier
… as IL-6 is crucial in the immunopathogenesis of COVID-19. Produced IL-6 and macrophage
… It has also been extensively studied as a possible therapeutic agent for the regulation of the …

[HTML][HTML] COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… α for treating COVID-19-related infections to manage COVID-19 and improve … therapeutic
agents are available. However, some supportive therapeutic interventions and anti-viral agents

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

J Alijotas-Reig, E Esteve-Valverde, C Belizna… - Autoimmunity …, 2020 - Elsevier
… related to Coronavirus-2 (SARS-CoV-2), coronavirus disease-2019 (COVID-19) may cause
… be considered as a potential therapeutic target against severe COVID-19. The relationship …

Molecular mechanisms and signaling pathways involved in immunopathological events of COVID-19

AA Peyvandi, S Niknazar, F Zare Mehrjerdi… - Physiology and …, 2021 - ppj.phypha.ir
… Harnessing the immune system to overcome cytokine storm and reduce viral load in covid-19:
a review of the phases of illness and therapeutic agents. Virol J 2020; 17: 1-18. https://doi.…

Pathogenesis guided therapeutic management of COVID-19: an immunological perspective

A Kumar, P Prasoon, PS Sekhawat… - … of Immunology, 2021 - Taylor & Francis
… on immunopathogenesis of COVID-19 and link that with the various therapeutic approaches
… article, we discuss in brief the basic immunology pertinent to the pathogenesis of COVID-19. …

A global picture: therapeutic perspectives for COVID-19

VP Chavda, C Kapadia, S Soni, R Prajapati… - …, 2022 - Future Medicine
… development of therapeutic agents is to design drug products to manage COVID-19 efficiently.
… The immunopathogenesis of COVID-19 is summarized in Figure 4; for more information …

[HTML][HTML] Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
… , and the factors affecting the immunopathology of COVID-19 and immune response against
the … that can be harnessed in developing effective therapeutic regimens against COVID-19. …