Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

SK Samrat, AM Tharappel, Z Li, H Li - Virus research, 2020 - Elsevier
vaccine against SARS-CoV or MERS-CoV have been tried with limited success. Since
SARS-CoV… the most preferred targets for making vaccines or therapeutics against SARS-CoV-2. In …

SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
… severity and ability to evade vaccine-induced and natural immunity. Here … SARS-CoV-2
structural and non-structural proteins and their impact on diagnostics, therapeutics and vaccines. …

[HTML][HTML] An evidence-based systematic review on emerging therapeutic and preventive strategies to treat novel coronavirus (SARS-CoV-2) during an outbreak …

AM Gudadappanavar, J Benni - … of Basic and Clinical Physiology and …, 2020 - degruyter.com
… the severity of SARS virus infections and to prevent or treat SARS virus–associated disease
[… weeks after immunization with the MNA delivered SARS-CoV-2, S1 subunit vaccine showed …

SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
… will only be contained when an efficient therapy or vaccine will become available. This …
SARS-CoV-2, the pathophysiology of the infection, the treatments currently tested, and vaccines

Current vaccine strategies against SARS-CoV-2: promises and challenges

D Kurup, J Myers, MJ Schnell - Journal of Allergy and Clinical Immunology, 2022 - Elsevier
… Here, we provide insight into the leading vaccines and their advantages and challenges…
SARS-CoV-2 spike protein and other issues that need to be addressed to overcome coronavirus

Updated approaches against SARS-CoV-2

H Li, Y Zhou, M Zhang, H Wang… - Antimicrobial agents and …, 2020 - Am Soc Microbiol
… the therapeutic drugs that directly target SARS-CoV-2 will be most effective. Besides, vaccines
… advances in deciphering SARS-Cov-2 will lead to additional potential therapeutic targets. …

Therapeutic opportunities to manage COVID-19/SARS-CoV-2 infection: Present and future

R Shetty, A Ghosh, SG Honavar… - Indian journal of …, 2020 - journals.lww.com
… against the SARS coronavirus family.[ 95 ] The second group of prophylactic agents may
constitute of factors that enhances the anti-viral host immune response such as Imiquimod (…

COVID-19: A review of therapeutic strategies and vaccine candidates

V Izda, MA Jeffries, AH Sawalha - Clinical Immunology, 2021 - Elsevier
… The leading mRNA SARS CoV-2 vaccine candidate is being developed as a collaboration
between the National Institute of Allergy and Infectious Diseases (NIAID) and Moderna. Their …

Potential therapeutic targets and promising drugs for combating SARSCoV‐2

H Zhou, Y Fang, T Xu, WJ Ni, AZ Shen… - British Journal of …, 2020 - Wiley Online Library
… , no specific vaccines or ideal drugs for SARS-CoV-2 have … drugs and vaccines to respond
to outbreaks of SARS-CoV-2 (… be good news regarding SARS-CoV-2 vaccines, as a result …

[HTML][HTML] Advances in the development of therapeutic strategies against COVID-19 and perspectives in the drug design for emerging SARS-CoV-2 variants

J Yin, C Li, C Ye, Z Ruan, Y Liang, Y Li, J Wu… - Computational and …, 2022 - Elsevier
therapeutic strategies against COVID-19, namely drugs targeting the SARS-CoV-2 life cycle
and SARS-CoV-2-… The development of above two strategies is implemented by repurposing …