Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… Both chronic infections and acute infections result in the induction of cytokine storms. It is
therefore becoming apparent that a combination therapy approach involving an antimicrobial …

The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine stormstherapeutic

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… Considering that acute lung injury is a characteristic finding in COVID-19, this study provides
a possible therapeutic approach to treating COVID-19 cytokine storm accompanied by lung …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… for therapy. Leveraging expert opinion, emerging evidence, and a case-… approach, this
position paper provides critical insights on cytokine storm from both a prognostic and therapeutic

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… of infection-induced cytokine storms are described from both … indicate that cytokine
storm-targeted therapies can effectively … many alternative therapeutic approaches for cytokine

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… known as cytokine release syndrome (CRS) or cytokine storm, is … timed anti-inflammatory
therapeutic strategies could improve … and nonpharmacological approaches to overcome the …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… and reliable approaches to counteract cytokine storm in … -cell therapy could help to distinguish
CRS from a cytokine storm (2)… laboratory criteria to identify the cytokine storm. In this review…

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

Potential therapeutic approaches for targeted inhibition of inflammatory cytokines following COVID-19 infection-induced cytokine storm

N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
therapies are now of interest in order to regulate the cytokine storm, and this review will
summarize and discuss advances in targeted therapies against cytokine storms induced by …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… main therapeutic approaches were comprehensively reviewed throughout the text. Therapies
focus … of immune system for cytokine storm control (IL-1 and IL-6 inhibitors, glucocorticoids, …