… strengthen the idea of rational therapeutic approach. In a case of … therapeutic margin of
anakinra and the central role of IL-1 in the cytokine storm merit reconsideration of this therapeutic …

… against the role of the cytokine storm in the pathology of clinical … of the cytokine storm and
immunomodulatory therapies to improve … of systems biology approaches to infectious disease …

… the cornerstone of a more novel therapeutic approach than common treatment methods,
featuring … presenting severe conditions due to the cytokine storm related to COVID-19 infection. …

… virus-induced pro-inflammatory cytokines. Successful therapy for this condition is currently
rare, … are the most often employed treatment approaches for viral infections. Unfortunately, no …

… modulation of production/signaling of oxidized phospholipids, and their potential as future
therapeutic options to ameliorate cytokine storm pathology during respiratory viral infection. …

… therapeutic drugs or vaccines are available to treat COVID-19. In this review, we intended to
describe how cytokine storm is … response due to cytokine storm during COVID-19 infection …

… -signaling and IFN therapy would favor the disease prognosis in COVID-19. … “cytokine
storm” induction and IFN antagonism during COVID-19 pathogenesis. Therapeutic approaches to …

… -inflammatory cytokines, referred to as cytokine storm. Interleukins, … Cytokine storm is defined
as acute overproduction and … for CRS and possible therapeutic approaches in this regard. …

… studies have determined some stereotypical cytokine patterns associated with disease state
… , cytokine targeted therapeutic approaches. Table 1 summarizes the key cytokines that are …

… In this review, we discussed the pathogenesis and consequences of cytokine storm along
with current therapeutic approaches and recommendations for its management in patients with …