Pharmacotherapeutics for cytokine storm in COVID-19

R Pal, MJ Chaudhary - Stem Cells, 2024 - Elsevier
… It can be triggered by various therapies, autoimmune … , and a case-based approach, this
chapter provides critical … nanoparticles can be a novel therapeutic approach for the treatment of …

Exhausted NK cells and cytokine storms in COVID-19: Whether NK cell therapy could be a therapeutic choice

M Ghasemzadeh, A Ghasemzadeh, E Hosseini - Human immunology, 2022 - Elsevier
… release syndrome (CRS) [172], its targeting with anti-IL-6R monoclonal antibodies (eg,
tocilizumab, sarilumab, siltuximab) is of main interest for therapeutic approach. In this regard, …

Are all cytokine storms the same?

N Panoskaltsis - Cancer Immunology, Immunotherapy, 2021 - Springer
… 2, the approach assumes that all cytokine storms are the same … of the pathogenic cytokines
in CRS, IL-6, with Tocilizumab … first- and second-line therapies for cytokine storm induced by …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
therapies and monoclonal antibodies cause cytokine release syndrome. Efforts are being
carried out to maximize the chance for therapeutic … on the inflammatory cytokine storm and its …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… Furthermore, cytokine storm can cause post-COVID-19 … in COVID-19-related cytokine storm
and its association with multi-… potential therapeutic targets to control cytokine storm wishing …

[HTML][HTML] … syndrome coronavirus-2 induces cytokine storm and inflammation during coronavirus disease 19: perspectives and possible therapeutic approaches

F Mannino, A Bitto, N Irrera - Frontiers in Pharmacology, 2020 - frontiersin.org
… to manage the several complications caused by an intense release of cytokines. This paper
reviews the current options on drugs used to reduce the deadly effects of the cytokine storm. …

Treatment of cytokine storm in COVID-19 patients with immunomodulatory therapy

L Yessayan, B Szamosfalvi, L Napolitano, B Singer… - Asaio …, 2020 - journals.lww.com
… The immunomodulatory effect of the SCD in the excessive inflammatory state and cytokine
storm differs from other current approaches to treat this dysregulated immunologic state. …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
cytokine levels while discussing cytokine sources and biological functions. Finally, we discuss
in brief potential therapies attempting to modulate the cytokine stormtherapeutic approach

Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
… Disruption of the CCL-5-CCR5 axis therefore seems an attractive therapeutic approach. An
open-label study (phase 2) is currently ongoing to establish whether one week of treatment …

Cytokine storm modulation in COVID-19: a proposed role for vitamin D and DPP-4 inhibitor combination therapy (VIDPP-4i)

MM Pinheiro, A Fabbri, M Infante - Immunotherapy, 2021 - Future Medicine
… of SARS-CoV-2, prevent disease progression and modulate the cytokine storm in COVID-19. …
approach to ratchet down the virulence of SARS-CoV-2 and modulate the cytokine storm in …