Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… targeted for therapy. Leveraging expert opinion, emerging evidence, and a case-based
approach, … critical insights on cytokine storm from both a prognostic and therapeutic standpoint. …

Introduction and overview of immunopathological mechanisms and future directions

SJ Pittock, B Giometto - Handbook of Clinical Neurology, 2024 - Elsevier
… As mechanisms are identified, a huge number of therapeutic options are available. Potential
… Newer and potentially important therapeutic approaches will likely include CAR-T therapies. …

A 21st century evil: immunopathology and new therapies of COVID-19

TF Silva, F Tomiotto-Pellissier, RA Sanfelice… - Frontiers in …, 2020 - frontiersin.org
… system during infection, in addition to discussing the main immunopathological mechanisms
involved in the development of the disease and potential new therapeutic approaches. …

Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications

A Allegra, M Di Gioacchino, A Tonacci… - International journal of …, 2020 - mdpi.com
… a comprehensive review of the immunopathology of Covid-19. … of other pathogen resistance
mechanisms. We fully address the … The therapeutic approaches used in the treatment of the …

Immunopathogenesis of inflammatory bowel disease and mechanisms of biological therapies

B Ahluwalia, L Moraes, MK Magnusson… - Scandinavian journal of …, 2018 - Taylor & Francis
… the way for several new biological therapies. This review will … with mechanisms of current
and emerging biological therapies. … An overview of the therapeutic approaches for IBD can be …

[PDF][PDF] Immunopathology of parasitic infections and therapeutic approaches in humans and animals

O Paciello, C Palmieri, I Otrocka-Domagala… - BioMed Research …, 2016 - biblio.ugent.be
… shown that the biological importance of IgE includes other mechanisms [1]. Cell-mediated
mechanisms of immunopathological lesions in parasitic diseases are mainly represented by …

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
… Based on the aforementioned pathophysiological and immunopathological considerations,
we provide a detailed overview of currently advocated repurposed drug therapies with …

Systemic lupus erythematosus: immunopathogenesis and novel therapeutic targets

E Beccastrini, MM D'Elios, G Emmi… - … Immunopathology …, 2013 - journals.sagepub.com
… The disclosure of novel mechanisms of SLE pathogenesis suggested new therapeutic
therapeutic approach based on a better understanding of the disease immunopathogenesis. …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… MicroRNAs and microRNA network targeting might be a useful technology to develop
faster and effective therapeutic approaches to treat hyperinflammatory responses generated …

[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
… , it describes how distinct immune mechanisms may affect the fate of SARS-CoV-2 infection.
… To date a possible therapeutic approach could involve an antiviral and a cell-entry inhibitor …