Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis

S Mahalanobish, S Saha, S Dutta, PC Sil - Pharmacological Research, 2020 - Elsevier
… Therefore, inhibition of these matrix metalloproteinases functions in IPF is a potential
therapeutic approach. In addition to the use of synthetic inhibitor, various natural compounds, gene …

Emerging therapeutic interventions for idiopathic pulmonary fibrosis

S Chakraborty, P Chopra, SV Ambi… - Expert opinion on …, 2014 - Taylor & Francis
… Another approach was to … therapeutic approaches has failed to establish its beneficial role
in the management of IPF. This is possibly due to the fact that none of the above therapeutic

New therapeutic approaches against pulmonary fibrosis

D Yu, Y Xiang, T Gou, R Tong, C Xu, L Chen… - Bioorganic …, 2023 - Elsevier
… of pulmonary fibrosis by anti-inflammatory therapy. Thus, the main cause of pulmonary
fibrosis is not inflammation, but inflammation has the possibility of developing fibrosis [6], [19]. …

Therapeutic approaches to organ fibrosis

TJ Franklin - The international journal of biochemistry & cell biology, 1997 - Elsevier
pulmonary fibrosis is … of fibrosis that show promise in experimental and clinical studies. In
the remainder of this review we shall look at the various phases of fibrosis and the therapeutic

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

KM Antoniou, A Pataka, D Bouros… - … & therapeutics, 2007 - Elsevier
… Although the above therapeutic approaches were efficient in animal models, the humans
could develop immune reactions against the antibodies or auto-immune-like disorders. …

Nintedanib: a novel therapeutic approach for idiopathic pulmonary fibrosis

IA Dimitroulis - Respiratory care, 2014 - rc.rcjournal.com
pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung disease with no clear etiology
and few therapeutic … of this disease might be important therapeutic targets. Nintedanib is a …

Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease

AL Mora, M Rojas, A Pardo, M Selman - Nature reviews Drug discovery, 2017 - nature.com
… In addition, we discuss current and potential future therapeutic approaches for this age-related
lung disease. The epidemiology, clinical presentation and diagnosis of IPF have recently …

Antifibrotic therapy for the treatment of pulmonary fibrosis

JA Lasky, LA Ortiz - The American journal of the medical sciences, 2001 - Elsevier
… of pulmonary fibrosis and has issued a summary statement of a recent workshop directed at
reviewing approaches … regarding novel therapies for pulmonary fibrosis including antifibrotic …

Fibrometabolism—An emerging therapeutic frontier in pulmonary fibrosis

B Selvarajah, I Azuelos, D Anastasiou… - Science Signaling, 2021 - science.org
therapies that improve survival. The application of omics technologies has revolutionized
our approach to identifying previously unknown therapeutic … new therapeutic approaches, …

Idiopathic pulmonary fibrosis: pathobiology of novel approaches to treatment

TM Maher - Clinics in chest medicine, 2012 - chestmed.theclinics.com
… The belief that the development and progression of IPF were driven by uncontrolled inflammation
underpins what has, until only recently, been the standard therapeutic approach for IPF…