… When pulmonary fibrosis predominates, ILDs are especially challenging to manage and
treat. Idiopathic pulmonary fibrosis (IPF), chronic hypersensitivity pneumonitis (cHP), and …

… approaches for the treatment of a particular fibrotic disorder, idiopathic pulmonary fibrosis
(IPF). … organs, so that the same therapeutic approaches may be applicable to many, if not all, …

… approaches to gene therapy. We then present an evaluation of published animal studies
to establish whether gene therapy could be a feasible therapeutic approach. … gene therapy …

… “standard” therapy of corticosteroids and cytotoxic medications is rarely effective, coupled
with new insights into pathogene— sis, has led to new therapeutic approaches that hold out …

… Several novel compounds are being developed in the perspective of a more targeted
therapeutic approach; in the meantime, the supportive care of these patients and their carers …

… defining markers of this fibrosis-associated gene cluster. To define CHIT1 role in fibrosis,
we used the therapeutic protocol of the bleomycin-induced pulmonary fibrosis mouse model. …

… describe the current therapies approved for the treatment of IPF and the emerging therapeutic
approaches. Currently, nintedanib and pirfenidone are the basis of IPF therapy, based on …

… using nucleic acid-based therapeutics is an emerging potential therapeutic approach in IPF,
to … to achieve highly specific and therapeutic effects. This approach has been successfully …

… pulmonary fibrosis (IPF). In addition to the approval and widespread availability of the first
IPF-specific therapies, … the possibility of personalized therapeutic approaches in the future. …

… these mediators in the pathogenesis of pulmonary fibrosis and also considers the possible
… Finally, potential novel therapeutic approaches are discussed, together with suggestions for …