Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… , do trigger life-threatening “cytokine storms” in the host which can … cytokine storms which
may prove useful in the clinic in the future and compare them to more traditional therapeutic

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… However, a meta-analysis of clinical trials indicated no clinical benefits of HCQ treatment
in … Early control of the cytokine storm through therapies, such as immunomodulators and …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… of therapeutic plasma exchange (TPE) to treat cytokine stormcytokines from the blood
and can improve cytokine storm 7 . … have demonstrated the clinical benefits of TPE in severe …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… T-cell therapy could help to distinguish CRS from a cytokine storm (2)… laboratory criteria to
identify the cytokine storm. In this review… corticosteroids might have some benefit for critically ill …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… underlying cytokine storm induction … cytokine storms are described from both host and
pathogen perspectives. In summary, current studies indicate that cytokine storm-targeted therapies

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - … and targeted therapy, 2021 - nature.com
… Reports of hemophagocytosis and clinical benefits from cytokine-targeted therapies in
severe COVID-19 patients further confirmed the existence and pathogenesis of COVID-CS. …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
therapies and monoclonal antibodies cause cytokine release syndrome. Efforts are being
carried out to maximize the chance for therapeutic benefit from … of sustained cytokine release. …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
cytokine storm is a hyperinflammatory state secondary to the excessive production of cytokines
… The term cytokine storm was first used in 1993 to describe the graft-versus-host disease …

[HTML][HTML] Agents to reduce cytokine storm

H Gerlach - F1000Research, 2016 - ncbi.nlm.nih.gov
therapeutic strategies and international guidelines for the management of hyperinflammation
during syndromes of cytokine storm … concerning the unclear risk-benefit ratio and high costs …