Cytokine storm syndrome: looking toward the precision medicine era

EM Behrens, GA Koretzky - Arthritis & rheumatology, 2017 - Wiley Online Library
… syndromes characterized by elevated levels of free IL-18 might benefit from such a therapy,
and this warrants further investigation. Although IL-33 is also an IL-1 family member, it is …

COVID-19 cytokine storm: targeting the appropriate cytokine

RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
therapies are being explored to dampen the cytokine storm … 19 cytokine storm syndrome was
targeting interleukin-6 (IL-6)… potential benefit in treating COVID-19 cytokine storm syndrome…

Immunoregulatory therapy strategies that target cytokine storms in patients with COVID‑19

X Wang, Z He, X Zhao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
… are required to explore the clinical benefits of blood purification for cytokine storms induced
by SARS-CoV-2 infection. Similarly, other factors for this therapy, such as the appropriate …

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
therapeutic drugs or vaccines are available to treat COVID-19. In this review, we intended to
describe how cytokine storm is … response due to cytokine storm during COVID-19 infection …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… a cytokine storm remains limited. In this review, we focus on the potential mechanisms
responsible for severe influenza-induced cytokine storm and the therapeutic … additional benefits

Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - International Journal of …, 2021 - mdpi.com
… Finally, it is noteworthy that in seriously ill COVID-19 patients, relevant therapeutic benefits
can be obtained by associating tocilizumab in combined treatments with corticosteroids, …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
… Hyperinflammation due to excessive cytokine release in … immunomodulatory candidates
for the cytokine release syndrome (… efficacy of both synthetic and natural therapeutic drugs for …

Potential therapeutic approaches for targeted inhibition of inflammatory cytokines following COVID-19 infection-induced cytokine storm

N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
… -2-induced cytokine storm grows, it will become more apparent what subset of patients and
at what disease stage could benefit the most from anti-inflammatory therapies. In parallel to …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… to choose a specific therapy and simultaneously measure the … In other words, applying the
right therapeutic approach at the … -designed therapeutic trials—otherwise, the potential benefit

[HTML][HTML] A “window of therapeutic opportunity” for anti-cytokine therapy in patients with coronavirus disease 2019

L De Stefano, F Bobbio-Pallavicini, A Manzo… - Frontiers in …, 2020 - frontiersin.org
… syndromes characterized by cytokine storms, such as the cytokine release syndrome (CRS), …
of therapeutic opportunity,” a phase of the disease during which the benefits of cytokine