… impeded the development of coronavirus specific therapeutics. … -CoV), has impelled the
development of such drugs. This review … The clinical development of optimized versions of such …

… in diagnosis, choice of therapeutic targets, development of drug candidates, and design of
… unlikely to be found and that the approach to drug development for this disorder needs to be …

… as T2DM advances, and insulin therapy is required if other agents are unable … treatment
algorithms for patients with T2DM and lessons from present therapies to inform the development …

… A fundamental barrier to the discovery and development of novel treatments for … is not
sufficient to predict the therapeutic value of novel drug targets. Thus, unvalidated targets are …

… In summary, gene therapy is a promising avenue for treatment of PD, and successful advances
have been made in dopamine restoration and symptomatic therapies, although disease …

… a strong focus on therapy development. These research efforts have led to the development
and recent … Finally, we discuss future directions and priorities for SMA therapy development. …

… is important when deciding when to subculture cells recovering from the drug treatment. …
clonal populations as drug-resistant models for is that there is no drug treatment is required and …

… market with new products and drugs highlights the massive need for an ideal wound healing
therapy, and the absence of the existence of such a treatment. Chronic wounds represent a …

… discovery and development of clinical candidates face significant challenges. Here, we …
state of development of HDAC therapeutics and their application for the treatment of human brain …

… 26 391 patients initiated on monotherapy with 1 of the 3 drugs, 4086 patients on dual oral
therapy, and 2346 patients on combination therapy with insulin, with an average follow-up of …