SARS-CoV-2 antiviral therapy

K Tao, PL Tzou, J Nouhin, H Bonilla… - Clinical microbiology …, 2021 - Am Soc Microbiol
… In conclusion, the main therapeutic advance during the pandemic has been the development
of highly potent neutralizing MAbs for the prevention and treatment of SARS-CoV-2. The …

Prevention and therapy of SARS-CoV-2 and the B. 1.351 variant in mice

DR Martinez, A Schäfer, SR Leist, D Li, K Gully… - Cell reports, 2021 - cell.com
… demonstrated therapeutic efficacy against SARS-CoV-2, the causative agent of coronavirus
… improve outcomes over single-agent therapies or whether antibody therapies will remain …

Evaluation of the safety profile and therapeutic efficacy of remdesivir in children with SARS-CoV-2 infection–a single-center, retrospective, cohort study

K Kautsch, J Wiśniowska… - European Journal of …, 2024 - Springer
… ) and Middle East respiratory syndrome coronavirus (MERS-CoV) was … therapeutic efficacy,
but its safety profile allowed the initiation of drug repurposing research, including SARS-CoV-…

… functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy …

CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres… - PLoS …, 2021 - journals.plos.org
… generation and characterization of a highly efficacious anti-SARS-CoV-2 IgG1 neutralizing
antibody, SC31. Significantly, we show that the therapeutic efficacy of SC31 is not solely due …

A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy

L Meng, J Zha, B Zhou, L Cao, C Jiang, Y Zhu… - PLoS …, 2023 - journals.plos.org
… importance, Ab08 shows therapeutic efficacy in SARS-CoV-2-… Together, our work identifies
a nAb with therapeutic potential … demonstrate therapeutic efficacy of Ab08 in SARS-CoV-2-…

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

J Huo, H Mikolajek, A Le Bas, JJ Clark… - Nature …, 2021 - nature.com
SARS-CoV-2 remains a global threat to human health … binding domain (RBD) of the
SARS-CoV-2 spike protein. Crystal … route showed potent therapeutic efficacy in the Syrian hamster …

Antiviral therapeutic approaches for SARS-CoV-2 infection: a systematic review

V Gil Martinez, A Avedillo Salas, S Santander Ballestin - Pharmaceuticals, 2021 - mdpi.com
efficacy against SARS and MERS, have been used in patients with COVID-19. This systematic
review aims to summarize evidence on the efficacy … in studies on SARS-CoV and MERS.; …

SARS-CoV-2: recent variants and clinical efficacy of antibody-based therapy

DD Singh, A Sharma, HJ Lee… - Frontiers in cellular and …, 2022 - frontiersin.org
… will evaluate the efficacy and safety of CERC002 in patients with severe SARS-CoV-2 for
28 … in hospitalized patients with mild to moderate SARS-CoV-2-associated pneumonia (ARDS) …

Cannabinoids for SARS-CoV-2 and is there evidence of their therapeutic efficacy?

A Onay, A Ertaş, V Süzerer, I Yener… - Turkish Journal of …, 2021 - journals.tubitak.gov.tr
… with viral diseases, especially SARS CoV-2, the impacts of cannabinoids in SARS-CoV-2
infection, as well as preclinical and clinical evidence of cannabinoid efficacy, and ends with the …

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug resistance …, 2020 - Elsevier
… , a novel SARS-CoV-2 coronavirus emerged, … efficacy against similar pathogens. Chloroquine,
remdesivir, lopinavir/ritonavir or ribavirin have all been successful in inhibiting SARS-CoV-…