A comprehensive review on rational and effective treatment strategies against an invisible enemy; SARS Cov-2 infection

G Aktas - Experimental Biomedical Research, 2020 - experimentalbiomedicalresearch …
… and possible treatment strategies against SARS Cov-2 infection. … In conclusion, mainstay
of the SARS Cov-2 treatment is general … Comparative therapeutic efficacy of remdesivir and …

[HTML][HTML] Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice

JH Jeong, S Chokkakula, SC Min, BK Kim, WS Choi… - Antiviral research, 2022 - Elsevier
… As such, we evaluated the therapeutic efficacy of NTV, RDV and MPV and their combinations
in SARS-CoV-2 infected K18-hACE2 transgenic mice and demonstrated the superior …

RNA‐dependent RNA polymerase of SARSCoV‐2 as a therapeutic target

Y Wang, V Anirudhan, R Du, Q Cui… - Journal of medical …, 2021 - Wiley Online Library
… In conclusion, although these drugs have potential as therapeutic options against SARS-CoV-2,
discovering and developing new drugs targeting the SARS-CoV-2 RdRp is urgently …

Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - … and Targeted Therapy, 2022 - nature.com
… The discovery of therapy reagents for treating COVID-19 are … SARS-CoV-2, a member of the
Orthocoronavirinae subfamily … and typically potential therapy agents that target SARS-CoV-2 …

[HTML][HTML] Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B. 1.1. 7 variant

AK Reuschl, LG Thorne, L Zuliani-Alvarez… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… and therapeutic interventions. We and others previously identified host-… therapies with
antiviral efficacy against SARS-CoV-2 infection. Less prone to the development of therapy

[HTML][HTML] Comprehensive analysis of drugs to treat SARSCoV‑2 infection: Mechanistic insights into current COVID‑19 therapies

GM Nitulescu, H Paunescu… - International …, 2020 - spandidos-publications.com
… These compounds could be a potential therapy in patients with SARS-CoV-2, provided
topical dosing and pharmacology afford adequate activation of respiratory ACE2. …

Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
SARS-CoV-2 proteins can … of SARS-CoV-2 from the whole viral particle to the individual
viral proteins and discuss their functions as well as their potential as targets for therapeutic

Vaccine development and therapeutic design for 2019‐nCoV/SARSCoV‐2: Challenges and chances

M Ghaebi, A Osali, H Valizadeh… - Journal of cellular …, 2020 - Wiley Online Library
… pseudovirus entry into target cells displaying high cross-neutralizing activity of the epitope
that give rise to the therapeutic efficacy of the vaccine. Therefore, learning from the study of …

[HTML][HTML] Exploring the future of SARS-CoV-2 treatment after the first two years of the pandemic: A comparative study of alternative therapeutics

BA Babalola, OS Akinsuyi, EO Folajimi, F Olujimi… - Biomedicine & …, 2023 - Elsevier
… a fresh perspective on alternative therapeutic approaches against SARS-CoV-2. Specifically,
… of action, efficacy, and clinical and economic considerations of these alternative therapies, …

Pharmacotherapeutics of SARS-CoV-2 infections

BD Kevadiya, J Machhi, J Herskovitz… - Journal of Neuroimmune …, 2021 - Springer
… syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for
SARS-CoV-2 … and preventative strategies being offered or soon to be developed for SARS-CoV-2. …