[HTML][HTML] Molecular perspectives of SARS-CoV-2: pathology, immune evasion, and therapeutic interventions

M Shah, HG Woo - Molecules and Cells, 2021 - Elsevier
… This review provides an update on the immunotherapeutic interventions implemented to …
current therapeutic interventions for COVID-19 with perspectives on their molecular mechanistic …

[HTML][HTML] Chaperone-dependent neurodegeneration: a molecular perspective on therapeutic intervention

A Carman, S Kishinevsky, J Koren III… - Journal of Alzheimer's …, 2013 - ncbi.nlm.nih.gov
… is regulated by the molecular chaperones. Under pathogenic … molecular chaperones
subsequently alter the fate of aberrant clients. Inhibition of Hsp90 and Hsc70, two major molecular

Metabolic syndrome: a clinical and molecular perspective

DE Moller, KD Kaufman - Annu. Rev. Med., 2005 - annualreviews.org
… Current therapies include diet and exercise as well as agents indicated for the treatment of …
Future therapies may accrue from the aggressive pursuit of newer molecular drug targets that …

Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons

S Vannucchi, MV Chiantore, G Mangino… - Current medicinal …, 2007 - ingentaconnect.com
… In this paper we focus on molecular bases of the IFN system … way to IFN clinical use based
on gene therapy or vaccine-like … new IFN-based therapeutic strategies to circumvent cancer …

Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives

S Mukherjee, R Patra, P Behzadi, A Masotti… - Frontiers in …, 2023 - frontiersin.org
… This review summarizes the current findings on the molecular and structural biology of TLRs
and gives an overview of the potency and promises of TLR-directed therapeutic strategies …

The molecular genetics of bone formation: implications for therapeutic interventions in bone disorders

PJ Marie - American Journal of Pharmacogenomics, 2001 - Springer
… be targeted for therapeutic intervention. Candidate approaches … new insight into the molecular
mechanisms that govern bone … of novel molecular targets for therapeutic interventions for …

Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
therapeutic interventions. These include prophylaxis to augment epithelial defense, reduce
viral load, and temper inflammatory injury, as well as therapeutics targeted toward molecular

A perspective on emerging therapeutic interventions for COVID-19

M Torequl Islam, M Nasiruddin, IN Khan… - Frontiers in public …, 2020 - frontiersin.org
… Adults (DisCoVeRy) study will be conducted in Europe by the National Institutes of Health 1
and Medical Research in France (Inserm), and it will include the same therapeutic molecules

New insights and potential therapeutic interventions in metabolic diseases

VJ Clemente-Suárez, A Martín-Rodríguez… - … Journal of Molecular …, 2023 - mdpi.com
… In the process of understanding metabolic diseases from a transdiagnostic perspective, it is
necessary to consider the role of psychological variables, with experiential avoidance being …

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020

H Hampel, S Lista, SJ Teipel, F Garaci, R Nisticò… - Biochemical …, 2014 - Elsevier
molecular mechanisms underlying various paths toward the pathogenesis of Alzheimer's
disease (AD) has begun to provide new insight for interventions … classes of therapeutic targets; …