… of mortality and morbidity in cytokine release syndrome (CRS) [9]… the processes which generate cytokinestorms are the same … involved in the generation of cytokinestorms in each of the …
… between cytokines, cell types, and signaling pathways are involved in cytokinestorm formation. The most important cells of the innate immune system involved in cytokinestorms' …
… SARS-CoV-2, the causative agent of COVID-19, attacks the immune system causing an exaggerated and uncontrolled release of pro-inflammatory mediators (cytokinestorm). Recent …
IA Clark, B Vissel - Seminars in immunopathology, 2017 - Springer
… , as well as focus on the therapeutic possibilities of this knowledge, which is a main theme of this text. We also extend the concept of a cytokinestorm into the chronic neurodegenerative …
… targeting of myeloid cells, and its potential therapeutic implications in the settings of hyperinflammatory responses such as cytokinestorms, driven by dysregulated immune responses to …
JK GUPTA - International Journal of Pharmaceutical …, 2021 - search.ebscohost.com
… of cytokinestorm is illegitimate immunotherapy during an infection or disease. Cytokinestorm … antibody and adoptive T-cell therapies can precipitate cytokinestorm. This type of situation …
P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
… In cytokinestorm syndromes, the subcutaneous route is often … in the management of cytokine storm syndromes and review the … improve the poor prognosis of cytokinestorm syndromes. …
F Mannino, A Bitto, N Irrera - Frontiers in Pharmacology, 2020 - frontiersin.org
… to manage the several complications caused by an intense release of cytokines. This paper reviews the current options on drugs used to reduce the deadly effects of the cytokinestorm. …
H Jia, E Neptune, H Cui - American journal of respiratory cell and …, 2021 - atsjournals.org
… The concerns over these uncertainties warrant vigilance in the design and application of pseudoligands for COVID-19 prevention and treatment in that a cytokinestorm has been …